Honey bee (Apis mellifera) gut microbiota promotes host endogenous detoxification capability via regulation of P450 gene expression in the digestive tract

• Published in: Microbial biotechnology Vol. 13; no. 4; pp. 1201 - 1212
• Main Authors: Wu, Yuqi, Zheng, Yufei, Chen, Yanan, Wang, Shuai, Chen, Yanping, Hu, Fuliang, Zheng, Huoqing
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.07.2020; John Wiley and Sons Inc; Wiley
• Subjects: Animals; Antibiotics; Apis mellifera; Bacteria; Bees; Cytochrome; Cytochrome P-450 Enzyme System - genetics; Cytochrome P-450 Enzyme System - metabolism; Cytochromes; Detoxification; Digestive system; Dysbacteriosis; Enzymes; Experiments; Fluvalinate; Food contamination & poisoning; Foraging behavior; Gastrointestinal Microbiome; Gastrointestinal tract; Gastrointestinal Tract - metabolism; Gene Expression; Gut microbiota; Honey; Inactivation, Metabolic; Insecticide resistance; Insecticides; Insects; Intestinal microflora; Metabolism; Metabolites; Microbiota; Midgut; Mortality; Pesticide residues; Pesticide resistance; Pesticides; Residues; Survival; Thiacloprid; Workers (insect caste); Xenobiotics

Summary There is growing number of studies demonstrating a close relationship between insect gut microbiota and insecticide resistance. However, the contribution of the honey bee gut microbiota to host detoxification ability has yet to be investigated. In order to address this question, we compared...