Mechanistic and phylogenetic insights into actinobacteria‐mediated oestrogen biodegradation in urban estuarine sediments

• Published in: Microbial biotechnology Vol. 14; no. 3; pp. 1212 - 1227
• Main Authors: Hsiao, Tsun‐Hsien, Chen, Yi‐Lung, Meng, Menghsiao, Chuang, Meng‐Rong, Horinouchi, Masae, Hayashi, Toshiaki, Wang, Po‐Hsiang, Chiang, Yin‐Ru
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.05.2021; John Wiley and Sons Inc; Wiley
• Subjects: Actinobacteria - genetics; Animals; Antibiotics; Bacteria; Biodegradation; Biodegradation, Environmental; Biomarkers; Biosphere; Carcinogens; Cholesterol; Cytochrome P450; Cytochromes P450; Dehydrogenases; Dioxygenase; Endocrine disruptors; Enzymes; Estrogens; Estrone; Estuaries; Genes; Genetic engineering; Genomes; Genomics; Geologic Sediments; Hydroxylase; Livestock; Manures; Metabolites; Microbial degradation; Microorganisms; Mineralization; Monooxygenase; Phylogeny; Rhodococcus; Sediments; Steroid hormones; Steroids

Summary Steroidal oestrogens are often accumulated in urban estuarine sediments worldwide at microgram per gram levels. These aromatic steroids have been classified as endocrine disruptors and group 1 carcinogens. Microbial degradation is a naturally occurring mechanism that mineralizes oestrogens i...