Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres - O'Sullivan, Roderick J; Kubicek, Stefan; Schreiber, Stuart L; Karlseder, Jan (Nature structural & molecular biology, 2010)
Keywords: 631/337/100/102; 631/337/103/560; 631/337/1427/2566; 631/337/641; Aging; Biochemistry; Biological Microscopy; Biomedical and Life Sciences; Biosynthesis; Bleomycin - toxicity; Cell cycle; Cell Line; Cellular biology; Cellular Senescence - physiology; Chromatin; Chromatin - metabolism; Chromatin Immunoprecipitation; Deoxyribonucleic acid; DNA; DNA Damage; DNA Replication; Epigenesis, Genetic; Fibroblasts - cytology; Fibroblasts - drug effects; Fibroblasts - metabolism; Genetic aspects; Histones; Histones - biosynthesis; Humans; Life Sciences; Membrane Biology; Methylation; Molecular biology; mRNA Cleavage and Polyadenylation Factors - biosynthesis; mRNA Cleavage and Polyadenylation Factors - genetics; Nuclear Proteins - biosynthesis; Nuclear Proteins - genetics; Oncogene Proteins, Viral - physiology; Papillomavirus E7 Proteins - physiology; Physiological aspects; Protein Processing, Post-Translational; Protein Structure; Repressor Proteins - physiology; Retinoblastoma Protein - physiology; Signal transduction; Telomere - physiology; Telomeres; Tumor Suppressor Protein p53 - physiology; United States