Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase–induced inflammation - Vukmanovic-Stejic, Milica; Chambers, Emma S.; Suárez-Fariñas, Mayte; Sandhu, Daisy; Fuentes-Duculan, Judilyn; Patel, Neil; Agius, Elaine; Lacy, Katie E.; Turner, Carolin T.; Larbi, Anis; Birault, Veronique; Noursadeghi, Mahdad; et al. (Journal of allergy and clinical immunology, 2018)
Keywords: Adult; Age; Aged; Aged, 80 and over; Aging; Aging - blood; Aging - immunology; Antigens; Antigens, Viral - immunology; Biopsy; C-reactive protein; C-Reactive Protein - analysis; CD4 antigen; CD4-Positive T-Lymphocytes - immunology; CD8 antigen; CD8-Positive T-Lymphocytes - immunology; Cell growth; Cytokines; Enzyme inhibitors; Erythema; Female; Herpesvirus 3, Human - immunology; Human subjects; Humans; Hypotheses; Immunity; Infections; Inflammation; Inflammation - blood; Inflammation - immunology; Interleukin 6; Interleukin-6 - blood; Kinases; Leukocytes; Lymphocytes T; Male; Malignancy; MAP kinase; Middle Aged; Monocytes; p38 mitogen-activated protein kinase; p38 Mitogen-Activated Protein Kinases - immunology; Peripheral blood; Protein kinase inhibitors; Proteins; Secretion; Skin; Skin - immunology; Studies; Tumor necrosis factor; Tumor Necrosis Factor-alpha - blood; Tumor necrosis factor-α; Vaccine efficacy; Varicella; varicella zoster virus; Young Adult; United Kingdom--UK; CRP; CBA; VZV; inflammation; DEG; Aging; varicella zoster virus; p38 mitogen-activated protein kinase; MAP; TRM; DC