Mesoporous Silica Nanomaterials: Versatile Nanocarriers for Cancer Theranostics and Drug and Gene Delivery

Mesoporous silica nanomaterials (MSNs) have made remarkable achievements and are being thought of by researchers as materials that can be used to effect great change in cancer therapies, gene delivery, and drug delivery because of their optically transparent properties, flexible size, functional sur...

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Published inPharmaceutics Vol. 11; no. 2; p. 77
Main Authors Kesse, Samuel, Boakye-Yiadom, Kofi Oti, Ochete, Belynda Owoya, Opoku-Damoah, Yaw, Akhtar, Fahad, Filli, Mensura Sied, Asim Farooq, Muhammad, Aquib, Md, Maviah Mily, Bazezy Joelle, Murtaza, Ghulam, Wang, Bo
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 13.02.2019
MDPI
Subjects
3003 Pharmaceutical Science
cancer theranostics
Cancer therapies
cancer therapy
Carbon Nanotubes
Cellular Uptake
Color Doppler Ultrasound
Contrast-Enhanced Ultrasound
drug delivery
Drug delivery systems
Efficient Sirna Delivery
Fatalities
gene therapy
In-Vitro
Intracellular Delivery
Magnetic resonance imaging
Mass-Spectrometry
Mesenchymal Stem-Cells
mesoporous silica nanomaterials
Oxide Nanoparticles
Pharmacy and materia medica
Review
RS1-441
stem cell
cancer therapy
gene therapy
cancer theranostics
drug delivery
stem cell
mesoporous silica nanomaterials
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Abstract Mesoporous silica nanomaterials (MSNs) have made remarkable achievements and are being thought of by researchers as materials that can be used to effect great change in cancer therapies, gene delivery, and drug delivery because of their optically transparent properties, flexible size, functional surface, low toxicity profile, and very good drug loading competence. Mesoporous silica nanoparticles (MSNPs) show a very high loading capacity for therapeutic agents. It is well known that cancer is one of the most severe known medical conditions, characterized by cells that grow and spread rapidly. Thus, curtailing cancer is one of the greatest current challenges for scientists. Nanotechnology is an evolving field of study, encompassing medicine, engineering, and science, and it has evolved over the years with respect to cancer therapy. This review outlines the applications of mesoporous nanomaterials in the field of cancer theranostics, as well as drug and gene delivery. MSNs employed as therapeutic agents, as well as their importance and future prospects in the ensuing generation of cancer theranostics and drug and therapeutic gene delivery, are discussed herein. Thus, the use of mesoporous silica nanomaterials can be seen as using one stone to kill three birds.
AbstractList Mesoporous silica nanomaterials (MSNs) have made remarkable achievements and are being thought of by researchers as materials that can be used to effect great change in cancer therapies, gene delivery, and drug delivery because of their optically transparent properties, flexible size, functional surface, low toxicity profile, and very good drug loading competence. Mesoporous silica nanoparticles (MSNPs) show a very high loading capacity for therapeutic agents. It is well known that cancer is one of the most severe known medical conditions, characterized by cells that grow and spread rapidly. Thus, curtailing cancer is one of the greatest current challenges for scientists. Nanotechnology is an evolving field of study, encompassing medicine, engineering, and science, and it has evolved over the years with respect to cancer therapy. This review outlines the applications of mesoporous nanomaterials in the field of cancer theranostics, as well as drug and gene delivery. MSNs employed as therapeutic agents, as well as their importance and future prospects in the ensuing generation of cancer theranostics and drug and therapeutic gene delivery, are discussed herein. Thus, the use of mesoporous silica nanomaterials can be seen as using one stone to kill three birds.
Mesoporous silica nanomaterials (MSNs) have made remarkable achievements and are being thought of by researchers as materials that can be used to effect great change in cancer therapies, gene delivery, and drug delivery because of their optically transparent properties, flexible size, functional surface, low toxicity profile, and very good drug loading competence. Mesoporous silica nanoparticles (MSNPs) show a very high loading capacity for therapeutic agents. It is well known that cancer is one of the most severe known medical conditions, characterized by cells that grow and spread rapidly. Thus, curtailing cancer is one of the greatest current challenges for scientists. Nanotechnology is an evolving field of study, encompassing medicine, engineering, and science, and it has evolved over the years with respect to cancer therapy. This review outlines the applications of mesoporous nanomaterials in the field of cancer theranostics, as well as drug and gene delivery. MSNs employed as therapeutic agents, as well as their importance and future prospects in the ensuing generation of cancer theranostics and drug and therapeutic gene delivery, are discussed herein. Thus, the use of mesoporous silica nanomaterials can be seen as using one stone to kill three birds.Mesoporous silica nanomaterials (MSNs) have made remarkable achievements and are being thought of by researchers as materials that can be used to effect great change in cancer therapies, gene delivery, and drug delivery because of their optically transparent properties, flexible size, functional surface, low toxicity profile, and very good drug loading competence. Mesoporous silica nanoparticles (MSNPs) show a very high loading capacity for therapeutic agents. It is well known that cancer is one of the most severe known medical conditions, characterized by cells that grow and spread rapidly. Thus, curtailing cancer is one of the greatest current challenges for scientists. Nanotechnology is an evolving field of study, encompassing medicine, engineering, and science, and it has evolved over the years with respect to cancer therapy. This review outlines the applications of mesoporous nanomaterials in the field of cancer theranostics, as well as drug and gene delivery. MSNs employed as therapeutic agents, as well as their importance and future prospects in the ensuing generation of cancer theranostics and drug and therapeutic gene delivery, are discussed herein. Thus, the use of mesoporous silica nanomaterials can be seen as using one stone to kill three birds.
Author Bazezy Joelle Maviah Mily
Muhammad Asim Farooq
Samuel Kesse
Yaw Opoku-Damoah
Bo Wang
Md Aquib
Mensura Sied Filli
Belynda Owoya Ochete
Ghulam Murtaza
Kofi Oti Boakye-Yiadom
Fahad Akhtar
AuthorAffiliation 5 Department of Pharmacy, COMSATS University Islamabad, Lahore Campus 54600, Pakistan; gmdogar356@gmail.com
3 Australian Institute for Bioengineering & Nanotechnology, The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia; yawdamoah@gmail.com
2 School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China; belyndaochete@yahoo.com
4 School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China; fahadakhtar121@outlook.com
1 Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China; kessejnr@yahoo.com (S.K.); otiboakye1000@gmail.com (K.O.B.-Y.); Biasfili@yahoo.com (M.S.F.); pharma1154@yahoo.com (M.A.F.); mdaquib0007@yahoo.com (M.A.); mmaviah@yahoo.fr (B.J.M.M.)
AuthorAffiliation_xml – name: 3 Australian Institute for Bioengineering & Nanotechnology, The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia; yawdamoah@gmail.com
– name: 2 School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China; belyndaochete@yahoo.com
– name: 4 School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China; fahadakhtar121@outlook.com
– name: 1 Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China; kessejnr@yahoo.com (S.K.); otiboakye1000@gmail.com (K.O.B.-Y.); Biasfili@yahoo.com (M.S.F.); pharma1154@yahoo.com (M.A.F.); mdaquib0007@yahoo.com (M.A.); mmaviah@yahoo.fr (B.J.M.M.)
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Issue 2
Keywords cancer therapy
gene therapy
cancer theranostics
drug delivery
stem cell
mesoporous silica nanomaterials
Language English
License https://creativecommons.org/licenses/by/4.0
Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
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Snippet Mesoporous silica nanomaterials (MSNs) have made remarkable achievements and are being thought of by researchers as materials that can be used to effect great...
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StartPage 77
SubjectTerms 3003 Pharmaceutical Science
cancer theranostics
Cancer therapies
cancer therapy
Carbon Nanotubes
Cellular Uptake
Color Doppler Ultrasound
Contrast-Enhanced Ultrasound
drug delivery
Drug delivery systems
Efficient Sirna Delivery
Fatalities
gene therapy
In-Vitro
Intracellular Delivery
Magnetic resonance imaging
Mass-Spectrometry
Mesenchymal Stem-Cells
mesoporous silica nanomaterials
Oxide Nanoparticles
Pharmacy and materia medica
Review
RS1-441
stem cell
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Title Mesoporous Silica Nanomaterials: Versatile Nanocarriers for Cancer Theranostics and Drug and Gene Delivery
URI https://cir.nii.ac.jp/crid/1873116917836392576
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Volume 11
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