Glutathione, glutathione peroxidase and some hematological parameters of HIV-seropositive subjects attending clinic in University of Calabar teaching hospital, Calabar, Nigeria

• Published in: BMC infectious diseases Vol. 19; no. 1; pp. 944 - 10
• Main Authors: Coco-Bassey, Stephen Bassey, Asemota, Enosakhare A., Okoroiwu, Henshaw Uchechi, Etura, Joyce E., Efiong, Esienanwan Esien, Inyang, Imeobong J., Uko, Emmanuel K.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 08.11.2019; BioMed Central; BMC
• Subjects: Adult; Anemia; Anemia - epidemiology; Anti-Retroviral Agents - therapeutic use; Antioxidants; Antioxidants (Nutrients); Antiretroviral agents; Blood tests; Calabar; CD4 Lymphocyte Count; Complete blood count; Enzyme-linked immunosorbent assay; Female; Glutathione; Glutathione - blood; Glutathione peroxidase; Glutathione Peroxidase - blood; Health aspects; Hemoglobins; Highly active antiretroviral therapy; HIV; HIV infections; HIV Infections - blood; HIV Infections - drug therapy; HIV Infections - epidemiology; HIV patients; HIV Seropositivity; Hospitals, University; Humans; Immune system; Infection; Male; Nigeria - epidemiology; Oxidative Stress; Peroxidase; Platelet Count; Prevalence; Public health; Public health movements; Sex Factors; T cells; Teachers; Thiols; Virus diseases; White blood cell count; Nigeria; Antioxidants; Glutathione peroxidase; HIV; Calabar; Glutathione

Despite the numerous intervention programmes, HIV still remains a public health concern with a high impact in Sub-Saharan Africa region. Oxidative stress has been documented in HIV subjects as viral infection promotes prolonged activation of immune system, hence, production of increased reactive oxy...