Airway macrophage-intrinsic TGF-β1 regulates pulmonary immunity during early-life allergen exposure - Branchett, William J.; Cook, James; Oliver, Robert A.; Bruno, Nicoletta; Walker, Simone A.; Stölting, Helen; Mack, Matthias; O’Garra, Anne; Saglani, Sejal; Lloyd, Clare M. (Journal of allergy and clinical immunology, 2021)
Keywords: Allergens; Allergens - immunology; Allergies; Animals; Asthma; Blocking antibodies; Bronchoscopy; CC chemokine receptors; CCR2 protein; CCR8 protein; CD11c antigen; chemokine; Chemokine receptors; Chemokines; Chemokines - immunology; Cloning; Environmental effects; Gene expression; Homeostasis; Human subjects; Hypersensitivity; Hypersensitivity - immunology; Immune response; Infections; Inflammation; Inhalation; Laboratory animals; Leukocytes (mononuclear); Lung - immunology; lung immunity; Lymphocytes T; macrophage; Macrophages; Macrophages, Alveolar - immunology; Maturation; Mechanisms of Allergy/Immunology; Mice; Mice, Inbred C57BL; Mice, Knockout; monocyte; Monocyte chemoattractant protein 1; Monocytes; neonate; Neonates; Newborn babies; Pathogens; Phagocytes; Phenotypes; Pyroglyphidae - immunology; Respiratory tract; Respiratory tract diseases; Software; TGF-β; Transforming Growth Factor beta1 - genetics; Transforming Growth Factor beta1 - immunology; Transforming growth factor-b1; type 2 immunity; United Kingdom--UK; Germany; chemokine; cDC; MP; AAD; IM; macrophage; neonate; AM; type 2 immunity; BAL; mLN; Asthma; HDM; ILC2; P; αCCR8; αCCR2; lung immunity; TGF-β; monocyte; T2