Rapid and simple identification of Beijing genotype strain of Mycobacterium tuberculosis using a loop-mediated isothermal amplification assay

• Published in: Microbiology and immunology Vol. 60; no. 7; p. 459
• Main Authors: Nagai, Yuhki, Iwade, Yoshito, Nakano, Manabu, Akachi, Shigehiro, Kobayashi, Takashi, Nishinaka, Takamichi
• Format: Journal Article
• Language: English
• Published: Australia 01.07.2016
• Subjects: Base Sequence; Gene Order; Genotype; Humans; Multiplex Polymerase Chain Reaction; Mycobacterium tuberculosis - classification; Mycobacterium tuberculosis - genetics; Nucleic Acid Amplification Techniques; Open Reading Frames; Reproducibility of Results; Sensitivity and Specificity; Tuberculosis - diagnosis; Tuberculosis - microbiology; Mycobacterium tuberculosis; loop-mediated isothermal amplification; Beijing genotype strain

Beijing genotype strains of Mycobacterium tuberculosis are geographically widespread and pose a notorious public health problem, these strains causing outbreaks of multidrug-resistant tuberculosis (TB); some studies have reported an association with drug resistance. Because the prevalence of Beijing...