Circulating microparticles, protein C, free protein S and endothelial vascular markers in children with sickle cell anaemia

• Published in: Journal of extracellular vesicles Vol. 4; no. 1; pp. 28414 - n/a
• Main Authors: Piccin, Andrea, Murphy, Ciaran, Eakins, Elva, Kunde, Jan, Corvetta, Daisy, Di Pierro, Angela, Negri, Giovanni, Guido, Mazzoleni, Sainati, Laura, Mc Mahon, Corrina, Smith, Owen Patrick, Murphy, William
• Format: Journal Article
• Language: English
• Published: Sweden Taylor & Francis 01.01.2015; John Wiley & Sons, Inc; Co-Action Publishing; Wiley
• Subjects: Adrenomedullin; Age; Anemia; Annexin V; Anticoagulants; Binding sites; Blood; Blood platelets; CD14 antigen; CD36 antigen; Chest; Children & youth; endothelin-1; Endothelins; Ethnicity; Flow cytometry; Funding; Heart attacks; Hemoglobin; Hydroxyurea; Methods; Microparticles; Minority & ethnic groups; Monoclonal antibodies; Nitric oxide; Original; Pediatrics; Plasma; Platelets; Protein C; Protein S; Proteins; sickle cell anaemia; Sickle cell anemia; Sickle cell disease; Studies; Tissue factor; Tumor necrosis factor-TNF; Italy; United Kingdom > UK; nitric oxide; adrenomedullin; microparticles; protein C; protein S; endothelin-1; sickle cell anaemia

Circulating microparticles (MP) have been described in sickle cell anaemia (SCA); however, their interaction with endothelial markers remains unclear. We investigated the relationship between MP, protein C (PC), free protein S (PS), nitric oxide (NO), endothelin-1 (ET-1) and adrenomedullin (ADM) in...