Repeated Morphine Prolongs Postoperative Pain in Male Rats
BACKGROUND:Opioids are effective postoperative analgesics. Disturbingly, we have previously reported that opioids such as morphine can worsen inflammatory pain and peripheral and central neuropathic pain. These deleterious effects are mediated by immune mediators that promote neuronal hyperexcitabil...
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Published in | Anesthesia and analgesia Vol. 128; no. 1; pp. 161 - 167 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
International Anesthesia Research Society
01.01.2019
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Subjects | |
Online Access | Get full text |
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