Cell Signaling Switches HOX-PBX Complexes from Repressors to Activators of Transcription Mediated by Histone Deacetylases and Histone Acetyltransferases

• Published in: Molecular and Cellular Biology Vol. 20; no. 22; pp. 8623 - 8633
• Main Authors: Saleh, Maya, Rambaldi, Isabel, Yang, Xiang-Jiao, Featherstone, Mark S.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.11.2000; Taylor & Francis
• Subjects: Acetyltransferases - metabolism; Animals; Binding Sites; Cell Line; CREB-Binding Protein; Cyclic AMP-Dependent Protein Kinases - metabolism; DNA-Binding Proteins - genetics; DNA-Binding Proteins - metabolism; Enhancer Elements, Genetic; Enzyme Inhibitors - pharmacology; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases - metabolism; Homeodomain Proteins - genetics; Homeodomain Proteins - metabolism; HOXB1 protein; Humans; Hydroxamic Acids - pharmacology; Mice; NCoR/SMRT protein; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; PBX1 protein; Pre-B-Cell Leukemia Transcription Factor 1; Promoter Regions, Genetic; Proto-Oncogene Proteins - genetics; Proto-Oncogene Proteins - metabolism; Repressor Proteins - genetics; Repressor Proteins - metabolism; Saccharomyces cerevisiae Proteins; Signal Transduction; SIN3B protein; Trans-Activators - genetics; Trans-Activators - metabolism; Transcription Factors - genetics; Transcription Factors - metabolism; Transcription, Genetic; Transcriptional Regulation; trichostatin

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