Germinal Center Kinase Is Required for Optimal Jun N-Terminal Kinase Activation by Toll-Like Receptor Agonists and Is Regulated by the Ubiquitin Proteasome System and Agonist-Induced, TRAF6-Dependent Stabilization - Zhong, Jian; Kyriakis, John M. (Molecular and Cellular Biology, 2004)
Keywords: Animals; CD40 Antigens - metabolism; Cell Growth and Development; Cell Line; Enzyme Activation; Humans; Interferon Inducers - metabolism; Interleukin-1 - metabolism; JNK Mitogen-Activated Protein Kinases - metabolism; Lipid A - metabolism; Lipopolysaccharides - metabolism; MAP Kinase Kinase Kinase 1 - metabolism; Membrane Glycoproteins - agonists; Membrane Glycoproteins - metabolism; Poly I-C - metabolism; Proteasome Endopeptidase Complex - metabolism; Proteasome Inhibitors; Protein-Serine-Threonine Kinases - genetics; Protein-Serine-Threonine Kinases - metabolism; Receptors, Cell Surface - agonists; Receptors, Cell Surface - metabolism; RNA Interference; Signal Transduction - physiology; TNF Receptor-Associated Factor 6 - metabolism; Toll-Like Receptors; Ubiquitin - metabolism