Balancing Selection Maintains a Form of ERAP2 that Undergoes Nonsense-Mediated Decay and Affects Antigen Presentation - Andrés, Aida M.; Dennis, Megan Y.; Kretzschmar, Warren W.; Cannons, Jennifer L.; Lee-Lin, Shih-Queen; Hurle, Belen; Schwartzberg, Pamela L.; Williamson, Scott H.; Bustamante, Carlos D.; Nielsen, Rasmus; Clark, Andrew G.; Green, Eric D. (PLoS genetics, 2010)
Keywords: African Continental Ancestry Group - genetics; Aminopeptidases - genetics; Aminopeptidases - immunology; Antigen Presentation; Asian Continental Ancestry Group - genetics; European Continental Ancestry Group - genetics; Evolutionary Biology/Human Evolution; Experiments; Gene Frequency; Genes; Genetic diversity; Genetics and Genomics/Bioinformatics; Genetics and Genomics/Genetics of the Immune System; Genetics and Genomics/Population Genetics; Genetics, Population; Genomes; Genotype; Haplotypes; Haplotypes - genetics; Histocompatibility Antigens Class I - immunology; Humans; Immune system; Immunology/Antigen Processing and Recognition; Immunology/Autoimmunity; Indians, North American - genetics; Minor Histocompatibility Antigens; Molecular Biology/RNA Splicing; Phylogeny; Polymorphism; Polymorphism, Single Nucleotide; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA Splicing; Selection, Genetic