Aggregation analysis of pharmaceutical human immunoglobulin preparations using size-exclusion chromatography and analytical ultracentrifugation sedimentation velocity - Krayukhina, Elena; Uchiyama, Susumu; Nojima, Kiyoko; Okada, Yoshiaki; Hamaguchi, Isao; Fukui, Kiichi (Journal of bioscience and bioengineering, 2013)
Keywords: Analytical ultracentrifugation sedimentation velocity; Biological and medical sciences; Biotechnology; Chromatography; Chromatography, Gel; computer software; drug formulations; drugs; Freeze Drying; Fundamental and applied biological sciences. Psychology; Gaussian skim; gel chromatography; Humans; Immunoglobulin; immunoglobulins; Immunoglobulins - analysis; Immunoglobulins - chemistry; Immunoglobulins - isolation & purification; integration; Japan; methods; pharmaceutical industry; quantitative analysis; Reproducibility of Results; Size-exclusion chromatography; Software; Ultracentrifugation; Vertical drop method; Japan; Analytical ultracentrifugation sedimentation velocity; Immunoglobulin; Size-exclusion chromatography; Gaussian skim; Vertical drop method; Aggregation; Human; Drug; Immunoglobulins; Method; Sedimentation; Chromatography