HLA genetic polymorphisms and prognosis of patients with COVID-19

• Published in: Medicina intensiva Vol. 45; no. 2; pp. 96 - 103
• Main Authors: Lorente, L., Martín, M.M., Franco, A., Barrios, Y., Cáceres, J.J., Solé-Violán, J., Perez, A., Marcos y Ramos, J.A., Ramos-Gómez, L., Ojeda, N., Jiménez, A., Lorente, Leonardo, Franco, Andrés, Barrios, Yvelise, Perez, Alina, Jiménez, Alejandro, Pérez-Cejas, Antonia, Pérez-Llombet, Alejandra, Uribe, Luis, González, Lourdes, Alvarez, Rocío, Martín, María M., Alcoba-Flórez, Julia, Estupiñan, Albano, Cáceres, Juan J., Vega, Paula, Gonzalez, Lucía, Solé-Violán, Jordi, Ojeda, Nazario, López, Sergio, Rodríguez-Pérez, Aurelio, Domínguez, Casimira, Marcos y Ramos, José Alberto, Zapata, María F., Ramos-Gómez, Luis, Ortiz-López, Raquel
• Format: Journal Article
• Language: English
• Published: Spain Elsevier España, S.L.U 01.03.2021; Elsevier España, S.L.U. y SEMICYUC
• Subjects: Aged; Alleles; APACHE; Case-Control Studies; COVID-19; COVID-19 - genetics; COVID-19 - mortality; Critical Care; Female; Genetic polymorphisms; Genetic Predisposition to Disease; Genotype; HLA; HLA Antigens - genetics; HLA-A3 Antigen; HLA-B39 Antigen - genetics; HLA-C Antigens - genetics; Humans; Intensive Care Units; Male; Middle Aged; Mortalidad; Mortality; Odds Ratio; Organ Dysfunction Scores; Original; Outcome; Polimorfismos genéticos; Polymorphism, Genetic; Preliminary Data; Prognosis; Pronóstico; Prospective Studies; Regression Analysis; Spain - epidemiology; Spain; COVID-19; Pronóstico; Mortality; Outcome; Polimorfismos genéticos; Mortalidad; HLA; Genetic polymorphisms

Different genetic polymorphisms of human leukocyte antigen (HLA) have been associated with the risk and prognosis of autoimmune and infectious diseases. The objectives of this study were to determine whether there is an association between HLA genetic polymorphisms and the susceptibility to and mort...