Mapping of meiotic recombination in human preimplantation blastocysts

• Published in: G3 : genes - genomes - genetics Vol. 13; no. 4
• Main Authors: Ma, Yuanlin, Wang, Jing, Li, Rong, Ding, Chenhui, Xu, Yan, Zhou, Canquan, Xu, Yanwen
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 11.04.2023
• Subjects: Blastocyst; Female; Fertilization in Vitro; Genetic testing; Genetic Testing - methods; Haplotypes; Homologous Recombination; Humans; Investigation; Phase transitions; Pregnancy; Preimplantation Diagnosis - methods; Translocation, Genetic; blastocyst; Han Chinese; meiosis; homologous recombination; reciprocal translocation; human

Abstract Recombination is essential for physical attachments and genetic diversity. The Han Chinese population is the largest ethnic group worldwide, therefore, the construction of a genetic map regarding recombination for the population is essential. In this study, 164 and 240 couples who underwent...