Association of gut microbiota with the pathogenesis of SARS-CoV-2 Infection in people living with HIV

• Published in: BMC microbiology Vol. 24; no. 1; pp. 6 - 17
• Main Authors: Ishizaka, Aya, Koga, Michiko, Mizutani, Taketoshi, Yamayoshi, Seiya, Iwatsuki-Horimoto, Kiyoko, Adachi, Eisuke, Suzuki, Yutaka, Kawaoka, Yoshihiro, Yotsuyanagi, Hiroshi
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 03.01.2024; BioMed Central; BMC
• Subjects: Age; Bacteria; Care and treatment; CD4 antigen; Colitis; Comparative analysis; Complications; Coronaviruses; COVID-19; COVID-19 - complications; Development and progression; Digestive system; Dysbacteriosis; Dysbiosis; Enteritis; Fatty acids; Gastrointestinal Microbiome; Gastrointestinal tract; Gut microbiota; Health aspects; Hepatitis A; HIV; HIV (Viruses); HIV Infections - complications; HIV patients; Homeostasis; Hospitals; Human immunodeficiency virus; Humans; Immunology; Infections; Inflammation; Inflammatory bowel disease; Intestinal microflora; Intestine; Long COVID; Lymphocytes; Lymphocytes T; Medical research; Medicine, Experimental; Microbiota; Microbiota (Symbiotic organisms); Microorganisms; Opportunist infection; Pathogenesis; Patients; Physiological aspects; Post-acute COVID-19 syndrome; Respiratory diseases; RNA; RNA, Ribosomal, 16S - genetics; rRNA 16S; SARS-CoV-2; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; T cells; Viral diseases; Japan; COVID-19; Microbiota; SARS-CoV-2; HIV; Post-acute COVID-19 syndrome

People living with HIV (PLWH) with chronic inflammation may have an increasing risk for coronavirus disease 2019 (COVID-19) severity; however, the impact of their gut microbiota on COVID-19 is not fully elucidated. Here, we analyzed the temporal changes in the gut microbiota composition of hospitali...