Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9 - Cohen, Jonathan; Pertsemlidis, Alexander; Kotowski, Ingrid K; Graham, Randall; Garcia, Christine Kim; Hobbs, Helen H (Nature genetics, 2005)
Keywords: Adult; Agriculture; Animal Genetics and Genomics; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Black or African American; Black People - genetics; Cancer Research; Care and treatment; Cholesterol; Cholesterol, LDL - blood; Codon, Nonsense; Control; Female; Fundamental and applied biological sciences. Psychology; Gene Function; Gene mutations; Genetic aspects; Genetics of eukaryotes. Biological and molecular evolution; Haplotypes; Human Genetics; Humans; Hypercholesterolemia; Identification and classification; letter; Low density lipoprotein receptors; Low density lipoproteins; Male; Middle Aged; Minority & ethnic groups; Mutation; Pedigree; Physiological aspects; Proprotein Convertase 9; Proprotein Convertases; Risk factors; Serine Endopeptidases - genetics; United States; Nonsense mutation; Cholesterol LDL; African