Exosomal long noncoding RNA HOTTIP as potential novel diagnostic and prognostic biomarker test for gastric cancer

• Published in: Molecular cancer Vol. 17; no. 1; pp. 68 - 5
• Main Authors: Zhao, Rui, Zhang, Yanli, Zhang, Xin, Yang, Yongmei, Zheng, Xin, Li, Xiaohui, Liu, Yingjie, Zhang, Yi
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 27.02.2018; BioMed Central; BMC
• Subjects: Biological markers; Biomarkers, Tumor; Development and progression; Diagnosis; Disease Progression; Exosomes - metabolism; Female; Gastric cancer; Gene Expression Regulation, Neoplastic; HOTTIP; Humans; Letter to the Editor; Long noncoding RNA; Male; Neoplasm Staging; Prognosis; RNA; RNA, Long Noncoding - genetics; ROC Curve; Stomach cancer; Stomach Neoplasms - diagnosis; Stomach Neoplasms - genetics; Stomach Neoplasms - metabolism; Stomach Neoplasms - mortality; HOTTIP; Prognosis; Diagnosis; Long noncoding RNA; Gastric cancer

Long noncoding RNA HOTTIP plays important roles in the generation and progression of human cancers. Exosomes participate in cellular communication by transmitting moleculars between cells and are regarded as suitable candidates for non-invasive diagnosis. However, the existence of HOTTIP in the circ...