SOLVe: a closed-loop system focused on protective mechanical ventilation

• Published in: Biomedical engineering online Vol. 22; no. 1; pp. 47 - 21
• Main Authors: von Platen, Philip, Pickerodt, Philipp A., Russ, Martin, Taher, Mahdi, Hinken, Lea, Braun, Wolfgang, Köbrich, Rainer, Pomprapa, Anake, Francis, Roland C. E., Leonhardt, Steffen, Walter, Marian
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 16.05.2023; BioMed Central; BMC
• Subjects: Acute respiratory distress syndrome; Animals; Automation; Care and treatment; Closed loop systems; Closed loops; Control algorithms; Customization; Diagnosis; Evidence, Expert; Feedback control; Gas exchange; Lung; Lungs; Mechanical ventilation; Medical research; Medicine, Experimental; Methods; Mortality; Oxygen content; Pandemics; Patient monitoring; Patient outcomes; Patients; Physiological aspects; Physiological closed-loop control; Physiology; Pilot Projects; Positive pressure respiration; Protective ventilation; Respiration; Respiration, Artificial; Respiratory distress syndrome; Respiratory Distress Syndrome - therapy; Tidal Volume - physiology; Ventilation; Ventilators; United Kingdom; Germany; Acute respiratory distress syndrome; Protective ventilation; Physiological closed-loop control

Mechanical ventilation is an essential component in the treatment of patients with acute respiratory distress syndrome. Prompt adaptation of the settings of a ventilator to the variable needs of patients is essential to ensure personalised and protective ventilation. Still, it is challenging and tim...