Gut microbes on the risk of advanced adenomas

• Published in: BMC microbiology Vol. 24; no. 1; pp. 264 - 14
• Main Authors: Jing, Zhuang, Zheng, Wu, Jianwen, Song, Hong, Shen, Xiaojian, Yu, Qiang, Wei, Yunfeng, Yin, Xinyue, Wu, Shuwen, Han, Feimin, Zhao
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 18.07.2024; BioMed Central; BMC
• Subjects: Adenoma - microbiology; Adenoma - virology; Advanced adenomas; Aged; Algorithms; Bacteria; Bacteria - classification; Bacteria - genetics; Bacteria - isolation & purification; Biological diversity; Biomarkers; Cancer; Care and treatment; Colonoscopy; Colorectal cancer; Colorectal Neoplasms - microbiology; Colorectal Neoplasms - virology; Comparative analysis; Composition; Data mining; Diagnosis; Enteroviruses; Escherichia coli; Feces; Feces - microbiology; Feces - virology; Female; Gastrointestinal Microbiome - genetics; Genomes; Gut bacteria; High-Throughput Nucleotide Sequencing; Homeostasis; Hospitals; Humans; Inflammatory bowel disease; Informed consent; Irritable bowel syndrome; Lipids; Machine Learning; Male; Metagenomic sequencing; Methods; Microbiota (Symbiotic organisms); Microorganisms; Middle Aged; Patient compliance; Patients; Prediction model; Prediction models; Prevention; Rectal polyps; Risk factors; Software; Tumors; Typing; Veganism; Viruses; Viruses - classification; Viruses - genetics; Viruses - isolation & purification; Viruses - pathogenicity; China; Enteroviruses; Gut bacteria; Advanced adenomas; Prediction model; Metagenomic sequencing

More than 90% of colorectal cancer (CRC) arises from advanced adenomas (AA) and gut microbes are closely associated with the initiation and progression of both AA and CRC. To analyze the characteristic microbes in AA. Fecal samples were collected from 92 AA and 184 negative control (NC). Illumina Hi...