New ribosome-inactivating proteins and other proteins with protein synthesis–inhibiting activities

• Published in: Applied microbiology and biotechnology Vol. 104; no. 10; pp. 4211 - 4226
• Main Authors: Wong, Jack Ho, Bao, Hui, Ng, Tzi Bun, Chan, Helen Hei Ling, Ng, Charlene Cheuk Wing, Man, Gene Chi Wai, Wang, Hexiang, Guan, Suzhen, Zhao, Shuang, Fang, Evandro Fei, Rolka, Krzysztof, Liu, Qin, Li, Chunman, Sha, Ou, Xia, Lixin
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.05.2020; Springer; Springer Nature B.V
• Subjects: Amino Acid Sequence; amino acid sequences; Amino acids; Animals; Anopheles; Antimicrobial peptides; Bacteria; barley; Benincasa hispida; Biomedical and Life Sciences; Biotechnology; Camphor; catalytic activity; Chains; Cinnamomum camphora; Corn; cucumbers; Cucurbita; Culex; Culicidae - chemistry; Deactivation; Domains; Flowering; Flowering plants; Fruit flies; Gourds; Insect Proteins - metabolism; Lagenaria siceraria; Lectins; Life Sciences; Luffa acutangula; Luffa aegyptiaca; macroalgae; mechanism of action; Medical colleges; Microbial Genetics and Genomics; Microbiology; Mini-Review; Molecular weight; Momordica charantia; Mosquitoes; Mushrooms; Peptides; Phytolacca; Pine needles; Pisum sativum subsp. sativum var. sativum; Plant Proteins - metabolism; Plants (botany); Pleurotus tuber-regium; Polyporus umbellatus; Proenzymes; Protein biosynthesis; Protein Biosynthesis - drug effects; Protein synthesis; Proteins; pumpkins; Ribonucleic acid; Ribosome Inactivating Proteins - classification; Ribosome Inactivating Proteins - metabolism; Ribosome Inactivating Proteins - pharmacology; ribosomes; RNA; Seeds; Seeds - chemistry; Shiga toxin; Snakes; Spiroplasma; Streptomyces coelicolor; Toxins; Trichosanthes cucumerina var. anguina; tubers; Volvariella volvacea; zymogens; Canada; Japan; China; Ribotoxins; Ribosome-inactivating proteins; Algal; Bacterial; Plant; Fungal; Mushroom

Ribosome-inactivating proteins (RIPs) consist of three varieties. Type 1 RIPs are single-chained and approximately 30-kDa in molecular weight. Type 2 RIPs are double-chained and composed of a type 1 RIP chain and a lectin chain. Type III RIPs, such as maize b-32 barley and JIP60 which are produced a...