Integrated analysis of lncRNA/circRNA–miRNA–mRNA in the proliferative phase of liver regeneration in mice with liver fibrosis

• Published in: BMC genomics Vol. 24; no. 1; pp. 417 - 12
• Main Authors: Wang, Qian, Long, Zhangtao, Zhu, Fengfeng, Li, Huajian, Xiang, Zhiqiang, Liang, Hao, Wu, Yachen, Dai, Xiaoming, Zhu, Zhu
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 24.07.2023; BioMed Central; BMC
• Subjects: Animals; Binomial distribution; Cell cycle; CircRNA; Circular RNA; Development and progression; Fibrosis; Gene expression; Genes; Genetic aspects; Genomes; Genomics; Health aspects; Hepatectomy; Identification and classification; Laboratory animals; Liver; Liver cancer; Liver Cirrhosis; Liver diseases; Liver fibrosis; Liver Regeneration; LncRNA; Mice; MicroRNAs; MiRNA; Molecular modelling; MRNA; Network analysis; Next-generation sequencing; Non-coding RNA; Regeneration; RNA; RNA, Circular; RNA, Long Noncoding; RNA, Messenger; Transcriptomes; China; United States > US; LncRNA; Liver fibrosis; MRNA; CircRNA; Liver regeneration; MiRNA

Non-coding RNAs play important roles in liver regeneration; however, their functions and mechanisms of action in the regeneration of fibrotic liver have not been elucidated. We aimed to clarify the expression patterns and regulatory functions of lncRNAs, circRNAs, miRNAs, and mRNAs in the proliferat...