Multiphoton microscopy for structure identification in human prostate and periprostatic tissue: implications in prostate cancer surgery

• Published in: BJU international Vol. 108; no. 9; pp. 1421 - 1429
• Main Authors: Tewari, Ashutosh K., Shevchuk, Maria M., Sterling, Joshua, Grover, Sonal, Herman, Michael, Yadav, Rajiv, Mudalair, Kumaran, Srivastava, Abhishek, Rubin, Mark A., Zipfel, Warren R., Maxfield, Frederick R., Xu, Chris, Webb, Watt W., Mukherjee, Sushmita
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.11.2011; Wiley-Blackwell; Wiley Subscription Services, Inc
• Subjects: Biological and medical sciences; Cancer surgery; Gynecology. Andrology. Obstetrics; histopathology; Humans; Imaging, Three-Dimensional - methods; Male; Male genital diseases; Medical sciences; Microscopy; Microscopy, Fluorescence, Multiphoton - methods; multiphoton microscopy; Nephrology. Urinary tract diseases; nerve sparing; Prospective Studies; Prostate - innervation; Prostate - pathology; Prostate - surgery; Prostate cancer; Prostatectomy - methods; Prostatic Neoplasms - pathology; Prostatic Neoplasms - surgery; real‐time imaging; Reproducibility of Results; robotic prostatectomy; Tumors; Tumors of the urinary system; Urinary tract. Prostate gland; Nephrology; Two photon microscopy; Prostate disease; robotic prostatectomy; Identification; Robotics; Urology; real-time imaging; Tissue; Conservative surgery; Histopathology; Telemedicine; multiphoton microscopy; Structure; Urogenital system; Male genital diseases; Human; Urinary system disease; Malignant tumor; Real time; nerve sparing; Anatomic pathology; Treatment; Medical imagery; Prostatectomy; Prostate cancer; Prostate; Cancer

Study Type – Diagnostic (exploratory cohort) Level of Evidence 2b What’s known on the subject? and What does the study add? Prostate cancer surgery outcomes depend on an optimal balance of three aspects: complete removal of cancerous glands, preservation of nerves for sexual function and of sphincte...