Plasma folate and total homocysteine levels are associated with the risk of myocardial infarction, independently of each other and of renal function

• Published in: Journal of internal medicine Vol. 266; no. 2; pp. 182 - 195
• Main Authors: Van Guelpen, B., Hultdin, J., Johansson, I., Witthöft, C., Weinehall, L., Eliasson, M., Hallmans, G., Palmqvist, R., Jansson, J.‐H., Winkvist, A.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.08.2009; Blackwell
• Subjects: acute myocardial infarction; Adult; Aged; Biological and medical sciences; blood; Cardiology. Vascular system; cardiovascular risk factors; cobalamin; Coronary heart disease; Dietary Supplements; etiology; Female; Folic Acid; Folic Acid - blood; Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi; Follow-Up Studies; Food Science; General aspects; Health Surveys; Heart; Homocysteine; Homocysteine - blood; Humans; Livsmedelsvetenskap; Male; Medical sciences; Middle Aged; Myocardial Infarction; Myocardial Infarction - blood; Myocardial Infarction - etiology; Natural Science; Naturvetenskap; Odds Ratio; Prospective Studies; Public Health, Global Health, Social Medicine and Epidemiology; renal function; Riboflavin; Riboflavin - blood; Risk; Sex Distribution; Sweden; Vitamin B 12; Vitamin B 12 - blood; Vitamin B 6; Vitamin B 6 - blood; Sweden; Myocardial infarction; Renal function; Vitamin; Cardiovascular disease; cardiovascular risk factors; Myocardial disease; Epidemiology; Folic acid; Folate; Blood plasma; Association; cobalamin; Homocystein; Kidney disease; homocysteine; Thiol; Urinary system disease; Nutrition; Acute; Coronary heart disease; Sulfur containing aminoacid; Medicine; Risk factor; Cardiovascular risk; Cobalamine; acute myocardial infarction

. Objectives.  To investigate the relationship between plasma folate, vitamin B12 and total homocysteine concentrations, dietary intake of folate and vitamins B12, B6 and B2, and the risk of first acute myocardial infarction (MI). Design.  Nested case‐referent study with up to 13 years of follow‐up....