The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response - Soulat, Didier; Bürckstümmer, Tilmann; Westermayer, Sandra; Goncalves, Adriana; Bauch, Angela; Stefanovic, Adrijana; Hantschel, Oliver; Bennett, Keiryn L; Decker, Thomas; Superti-Furga, Giulio (The EMBO journal, 2008)
Keywords: Amino Acid Sequence; Cell Line; Chromatin; DDX3X; DEAD-box RNA Helicases - genetics; DEAD-box RNA Helicases - metabolism; DEAD-box RNA Helicases - physiology; EMBO19; EMBO37; Genetics; Humans; Immune response; Immunity, Innate; innate immunity; interferon; Interferon Type I - biosynthesis; Interferon Type I - genetics; Interferon Type I - immunology; Kinases; Listeria monocytogenes; Listeria monocytogenes - physiology; Listeriosis - immunology; Listeriosis - metabolism; Models, Molecular; Molecular biology; Molecular Sequence Data; Mutation; Pathogens; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Serine-Threonine Kinases - metabolism; Protein Serine-Threonine Kinases - physiology; TBK1; DDX3X; TBK1; innate immunity; interferon; phosphorylation