Single-cell transcriptome identifies molecular subtype of autism spectrum disorder impacted by de novo loss-of-function variants regulating glial cells - Nassir, Nasna; Bankapur, Asma; Samara, Bisan; Ali, Abdulrahman; Ahmed, Awab; Inuwa, Ibrahim M.; Zarrei, Mehdi; Safizadeh Shabestari, Seyed Ali; AlBanna, Ammar; Howe, Jennifer L.; Berdiev, Bakhrom K.; Scherer, Stephen W.; et al. (Human genomics, 2021)
Keywords: Animals; Autism; Autism spectrum disorder; Autism Spectrum Disorder - genetics; Brain; Brain tissue; Cortex (cingulate); Cortex (temporal); De novo LOF variant; Exons; Gene expression; Gene Expression Regulation; Gene mapping; Gene regulation; Genomes; Glial cell type; Glial cells; Mice; Mutation; Nerve Tissue Proteins - genetics; Neuroglia - pathology; Neuronal-glial interactions; Prefrontal cortex; Primary Research; Receptors, Cell Surface - genetics; Single-cell transcriptomics; Temporal gyrus; Transcription; Transcriptome - genetics; Transcriptomes; Visual cortex; Single-cell transcriptomics; De novo LOF variant; Glial cell type; Brain tissue; Autism spectrum disorder