The basic characteristics of extracellular vesicles and their potential application in bone sarcomas

• Published in: Journal of nanobiotechnology Vol. 19; no. 1; pp. 277 - 12
• Main Author: Li, Shenglong
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 17.09.2021; BioMed Central; BMC
• Subjects: Angiogenesis; Apoptosis; Biological activity; Biomarkers; Biomarkers - metabolism; Biomedical materials; Biosynthesis; Body fluids; Bone cancer; Bone Neoplasms - diagnosis; Bone Neoplasms - pathology; Bone sarcomas; Bone tumors; Breast milk; Cancer diagnosis; Cancer therapy; Care and treatment; Cell interaction; Cell interactions; Cell organelles; Chemotherapy; Chondrosarcoma; Collagen Type VI - metabolism; Communication; Deoxyribonucleic acid; Development and progression; Diagnosis; DNA; Endothelial cells; Ewing's sarcoma; Ewings sarcoma; Extracellular matrix; Extracellular vesicles; Extracellular Vesicles - genetics; Extracellular Vesicles - metabolism; Fibroblasts; Flow cytometry; Health aspects; Heat shock proteins; Humans; Immune system; Invasion and metastasis; Lipids; Medical prognosis; Membrane vesicles; Mesenchyme; Metabolites; Metastases; Metastasis; Microenvironments; MicroRNAs - metabolism; Microscopy; miRNA; mRNA; Osteoclasts; Osteosarcoma; Osteosarcoma - diagnosis; Osteosarcoma - pathology; Physiological aspects; Physiology; Prognosis; Review; Ribonucleic acid; RNA; Saliva; Sarcoma; Scalp; Spinal cord; Stem cells; Teenagers; Tumor Microenvironment; Tumors; Vesicles; China; Extracellular vesicles; Cancer diagnosis; Bone sarcomas; Cancer therapy; Invasion and metastasis

Bone sarcomas are rare cancers accompanied by metastatic disease, mainly including osteosarcoma, Ewing sarcoma and chondrosarcoma. Extracellular vesicles (EVs) are membrane vesicles released by cells in the extracellular matrix, which carry important signal molecules, can stably and widely present i...