An anti-perfringolysin O monoclonal antibody cross-reactive with streptolysin O protects against streptococcal toxic shock syndrome - Matsumura, Takayuki; Nishiyama, Ayae; Aiko, Michio; Ainai, Akira; Ikebe, Tadayoshi; Chiba, Joe; Ato, Manabu; Takahashi, Yoshimasa (BMC research notes, 2020)
Keywords: Animals; Antibiotics; Antibodies, Monoclonal; Bacteria; Bacterial Proteins; Bacterial Toxins; Care and treatment; Cholesterol; Cholesterol-dependent cytolysins; Clinical isolates; Cross-reactivity; Cytolysins; Experiments; Hemolysin Proteins; Infections; Infectious diseases; Leukocytes (neutrophilic); Medical prognosis; Mice; Mice, Inbred C57BL; Monoclonal antibodies; Neutralizing monoclonal antibody; Neutrophils; Perfringolysin O; Prevention; Research Note; Septic shock; Shock, Septic - drug therapy; Shock, Septic - prevention & control; Statistical analysis; Streptococcal Infections - drug therapy; Streptococcal Infections - prevention & control; Streptococcal toxic shock syndrome; Streptococcus; Streptococcus pyogenes; Streptolysin O; Streptolysins; Testing; Toxic shock syndrome; Virulence; Working groups; Japan; United Kingdom--UK; Cholesterol-dependent cytolysins; Perfringolysin O; Streptolysin O; Neutralizing monoclonal antibody; Streptococcal toxic shock syndrome