Distribution, characterization, and antibiotic resistance of hypervirulent Klebsiella pneumoniae isolates in a Chinese population with asymptomatic bacteriuria

• Published in: BMC microbiology Vol. 22; no. 1; pp. 29 - 9
• Main Authors: Li, Jun, Li, Yanbing, Tang, Mengli, Xia, Fengjun, Min, Changhang, Hu, Yongmei, Wang, Haichen, Zhang, Jingyi, Zou, Mingxiang
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 18.01.2022; BioMed Central; BMC
• Subjects: Adult; Animals; Antibiotic resistance; Antibiotics; Antiinfectives and antibacterials; Antimicrobial agents; Antimicrobial susceptibility; Asians; Asymptomatic; Asymptomatic bacteriuria; Asymptomatic Infections - epidemiology; Bacteremia; Bacteria in the urine; Bacterial infections; Bacteriuria; Bacteriuria - epidemiology; Biofilm formation; Biofilms; Biofilms - growth & development; Causes of; Distribution; Drug resistance; Drug resistance in microorganisms; Drug Resistance, Multiple, Bacterial; Epidemiology; Female; Genetic aspects; Genetic relationship; Hospitals; Humans; Hypervirulent K. pneumoniae; Identification and classification; Klebsiella; Klebsiella infections; Klebsiella Infections - epidemiology; Klebsiella Infections - ethnology; Klebsiella Infections - microbiology; Klebsiella Infections - urine; Klebsiella pneumoniae; Klebsiella pneumoniae - drug effects; Klebsiella pneumoniae - genetics; Klebsiella pneumoniae - pathogenicity; Larva - microbiology; Male; Medical research; Medicine, Experimental; Microbial Sensitivity Tests; Middle Aged; Minimum inhibitory concentration; Moths - microbiology; Nosocomial infection; Nosocomial infections; Phylogeny; Population; Serotypes; Survival; Urinary tract; Urinary tract diseases; Urinary tract infections; Urine; Urogenital system; Virulence; Virulence (Microbiology); Virulence Factors - genetics; Virulence-associated genes; Whole genome sequencing; Whole-genome sequencing (WGS); China; Asymptomatic bacteriuria; Antimicrobial susceptibility; Virulence-associated genes; Whole-genome sequencing (WGS); Biofilm formation; Hypervirulent K. pneumoniae

Asymptomatic bacteriuria (ASB) frequently occurs among all ages and may develop into urinary tract infections (UTIs). Hypervirulent Klebsiella pneumoniae (hvKP) has become a new threat to human health. In our study, we aimed to investigate the epidemiological characteristics of hvKP in population wi...