Weight shapes the intestinal microbiome in preterm infants: results of a prospective observational study

• Published in: BMC microbiology Vol. 21; no. 1; pp. 219 - 12
• Main Authors: Heida, Fardou H., Kooi, Elisabeth M. W., Wagner, Josef, Nguyen, Thi-Yen, Hulscher, Jan B. F., van Zoonen, Anne G. J. F., Bos, Arend F., Harmsen, Hermie J. M., de Goffau, Marcus C.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 21.07.2021; BioMed Central; BMC
• Subjects: Babies; Bacilli; Bacteria - classification; Bacteria - genetics; Biodiversity; Birth size; Birth Weight; Body Weight; Cesarean section; Children; Composition; Development; E coli; Feces; Feces - microbiology; Gastrointestinal Microbiome - genetics; Gestational age; Health aspects; Humans; Infant, Newborn; Infant, Premature; Infants; Infants (Premature); Intestinal microbiome; Intestine; Meconium; Microbiomes; Microbiota (Symbiotic organisms); Mode of delivery; Neonates; Newborn babies; Observational studies; Pediatric research; Physiological aspects; Placenta; Premature babies; Prematurity; Regression analysis; RNA, Ribosomal, 16S - genetics; rRNA; Sampling; Staphylococcus; Vagina; Weight; Netherlands; Development; Intestinal microbiome; Mode of delivery; Prematurity; Weight

The intestinal microbiome in preterm infants differs markedly from term infants. It is unclear whether the microbiome develops over time according to infant specific factors. We analysed (clinical) metadata - to identify the main factors influencing the microbiome composition development - and the f...