Aloe derived nanovesicle as a functional carrier for indocyanine green encapsulation and phototherapy

• Published in: Journal of nanobiotechnology Vol. 19; no. 1; pp. 439 - 24
• Main Authors: Zeng, Lupeng, Wang, Huaying, Shi, Wanhua, Chen, Lingfan, Chen, Tingting, Chen, Guanyu, Wang, Wenshen, Lan, Jianming, Huang, Zhihong, Zhang, Jing, Chen, Jinghua
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 20.12.2021; BioMed Central; BMC
• Subjects: Aloe; Aloe - chemistry; Aloe - metabolism; Aloe derived nanovesicles; Analysis; Animals; Antioxidants; Antioxidants - chemistry; Biocompatibility; Cancer; Cancer therapies; Cancer therapy; Care and treatment; Cell culture; Cell Line, Tumor; Cell Proliferation - drug effects; Centrifugation; Cytokines - blood; Diagnosis; Drug administration; Drug carriers; Drug delivery; Drug delivery systems; Drug resistance; Drug Stability; Drugs; Hemolysis - drug effects; Humans; Indocyanine green; Indocyanine Green - chemistry; Indocyanine Green - pharmacology; Indocyanine Green - therapeutic use; Lipids; Liposomes - chemistry; Melanoma; Melanoma, Experimental - drug therapy; Methods; Mice; Nanoparticles; Nanostructures - chemistry; Nanostructures - therapeutic use; Nanostructures - toxicity; Particle Size; Patient outcomes; Phototherapy; Phytochemicals; Production costs; Risk factors; Shelf life; Stability; Storage stability; Toxicity; Vehicles; Viscosity; China; Drug carriers; Indocyanine green; Stability; Cancer therapy; Aloe derived nanovesicles

Cancer is one of the devastating diseases in the world. The development of nanocarrier provides a promising perspective for improving cancer therapeutic efficacy. However, the issues with potential toxicity, quantity production, and excessive costs limit their further applications in clinical practi...