The acid-sensing ion channel 2 (ASIC2) of ciliated cells in the developing rat nasal septum

• Published in: Archives of Histology and Cytology Vol. 73; no. 2; pp. 81 - 89
• Main Authors: Kikuchi, Shin, Ninomiya, Takafumi, Kawamata, Tomoyuki, Ogasawara, Noriko, Kojima, Takashi, Tachi, Nobutada, Tatsumi, Haruyuki
• Format: Journal Article
• Language: English
• Published: Japan International Society of Histology and Cytology 01.01.2010; Japan Science and Technology Agency
• Subjects: Acid Sensing Ion Channels; Animals; Cilia - metabolism; Gene Expression Regulation, Developmental; Immunohistochemistry; Nasal Mucosa - cytology; Nasal Mucosa - metabolism; Nasal Septum - cytology; Nasal Septum - embryology; Nasal Septum - metabolism; Nasal Septum - ultrastructure; Nerve Tissue Proteins - genetics; Nerve Tissue Proteins - metabolism; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Sodium Channels - genetics; Sodium Channels - metabolism

The airway epithelium is exposed to an acidic environment in certain conditions. The acid-sensing ion channel 2 (ASIC2) belongs to the epithelial amiloride-sensitive sodium channel and degenerin (ENaC/DEG) family and is expressed on cilia of the respiratory epithelium. The aim of this study was to d...