Novel brain-targeted nanomicelles for anti-glioma therapy mediated by the ApoE-enriched protein corona in vivo - Zhang, Zhe-Ao; Xin, Xin; Liu, Chao; Liu, Yan-hong; Duan, Hong-Xia; Qi, Ling-ling; Zhang, Ying-Ying; Zhao, He-ming; Chen, Li-Qing; Jin, Ming-Ji; Gao, Zhong-Gao; Huang, Wei (Journal of nanobiotechnology, 2021)
Keywords: Analysis; ApoE protein corona; Apolipoprotein E; Apolipoproteins; Apoptosis; Binding; Binding sites; Bioaccumulation; Biological properties; Blood-brain barrier; Brain cancer; Brain tumors; Care and treatment; Cell proliferation; Controlled release; Diagnosis; Dosage and administration; Drug delivery; Drug delivery systems; Drug development; Drugs; Efficiency; Endothelial cells; Enrichment; Glioma; Gliomas; Health aspects; Lipids; Low density lipoprotein receptors; Methods; Nanoparticles; NMR; Nuclear magnetic resonance; Paclitaxel; Peptides; Permeability; Physicochemical properties; Plasma proteins; Protein interaction; Proteins; Receptor density; Receptors; Risk factors; Sonication; Targeting therapy; Tumors; Umbilical vein; Vehicles; Western blotting; Zeta potential; β-Amyloid; China; Glioma; ApoE protein corona; Paclitaxel; Targeting therapy