TMT-based quantitative proteomics analysis of the effects of Jiawei Danshen decoction myocardial ischemia-reperfusion injury

• Published in: Proteome science Vol. 20; no. 1; p. 17
• Main Authors: Zhu, Xiang-Mei, Tan, Yang, Shi, Yu-He, Li, Qing, Zhu, Jue, Liu, Xiang-Dan, Tong, Qiao-Zhen
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 14.12.2022; BioMed Central; BMC
• Subjects: Analysis; Biochemical markers; Bioinformatics; Cardiovascular disease; Casualties; Chinese medicine; Coronary artery disease; Coronary heart disease; Coronary vessels; Dehydrogenases; DNA-directed RNA polymerase; Experiments; Genomes; Genomics; Health aspects; Heart; Heart diseases; Heart surgery; Herbal medicine; Ischemia; Jiawei Danshen decoction (JWDSD); Kinases; Laboratory animals; Leukocytes (neutrophilic); Linoleic acid; Lymphocytes T; Medical research; Medicine, Chinese; Metastases; Molecular modelling; Myocardial ischemia; Myocardial ischemia-reperfusion injury (MIRI); Non-Hodgkin's lymphomas; Ostomy; Oxidative stress; Peptides; Prognosis; Proteins; Proteomic; Proteomics; Rankings; Raw materials; Reperfusion; Reperfusion injury; Scientific equipment and supplies industry; T cells; T-cell lymphoma; Tandem mass tag (TMT); Tiam1 protein; Traditional Chinese medicine (TCM); Unsaturated fatty acids; Western blotting; United States; China; Tandem mass tag (TMT); Jiawei Danshen decoction (JWDSD); Myocardial ischemia-reperfusion injury (MIRI); Traditional Chinese medicine (TCM); Proteomic

Every year, approximately 17 million people worldwide die due to coronary heart disease, with China ranking second in terms of the death toll. Myocardial ischemia-reperfusion injury (MIRI) significantly influences cardiac function and prognosis in cardiac surgery patients. Jiawei Danshen Decoction (...