A novel miR-375-HOXB3-CDCA3/DNMT3B regulatory circuitry contributes to leukemogenesis in acute myeloid leukemia - Bi, Laixi; Zhou, Bin; Li, Haiying; He, Licai; Wang, Chunjing; Wang, Zhonggai; Zhu, Liqing; Chen, Mengqian; Gao, Shenmeng (BMC cancer, 2018)
Keywords: 3' Untranslated Regions - genetics; Acute Disease; Acute myelocytic leukemia; Adult; AML; Animals; Carcinogenesis - genetics; Carcinogenesis - metabolism; Cell Cycle Proteins - genetics; Cell Cycle Proteins - metabolism; Cell Line, Tumor; Development and progression; DNA (Cytosine-5-)-Methyltransferases - genetics; DNA (Cytosine-5-)-Methyltransferases - metabolism; DNA hypermethylation; DNA Methyltransferase 3B; DNMT3B; Female; Gene expression; Gene Expression Regulation, Leukemic; Genetic aspects; HL-60 Cells; Homeodomain Proteins - genetics; Homeodomain Proteins - metabolism; HOXB3; Humans; K562 Cells; Kaplan-Meier Estimate; Leukemia, Myeloid - genetics; Leukemia, Myeloid - metabolism; Leukemia, Myeloid - pathology; Male; Mice, Inbred NOD; Mice, Knockout; Mice, Nude; Mice, SCID; MicroRNA; MicroRNAs - genetics; Middle Aged; miR-375; Myeloid leukemia; Transplantation, Heterologous; Young Adult; AML; DNMT3B; DNA hypermethylation; HOXB3; miR-375