Multiple copies of the oxytetracycline gene cluster in selected Streptomyces rimosus strains can provide significantly increased titers - Pikl, Špela; Carrillo Rincón, Andrés Felipe; Slemc, Lucija; Goranovič, Dušan; Avbelj, Martina; Gjuračić, Krešimir; Sucipto, Hilda; Stare, Katja; Baebler, Špela; Šala, Martin; Guo, Meijin; Luzhetskyy, Andriy; et al. (Microbial cell factories, 2021)
Keywords: Bioactive compounds; Biological activity; Biosynthesis; Biosynthetic gene cluster; Chromosomes; Cloning; Deoxyribonucleic acid; DNA; Engineering; Enzymes; Gene expression; Genetic aspects; Industrial microorganisms; Metabolic engineering; Metabolism; Metabolites; Microbiological research; Microbiological synthesis; Microorganisms; Natural products; Oxytetracycline; Physiological aspects; Production processes; Reproducibility; Stability; Streptomyces; Streptomyces rimosus; Yeast; ΦC31; Slovenia; Oxytetracycline; Streptomyces rimosus; ΦC31; Biosynthesis; Biosynthetic gene cluster