Environmental chemicals, breast cancer progression and drug resistance

• Published in: Environmental health Vol. 19; no. 1; pp. 117 - 25
• Main Authors: Koual, Meriem, Tomkiewicz, Céline, Cano-Sancho, German, Antignac, Jean-Philippe, Bats, Anne-Sophie, Coumoul, Xavier
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 17.11.2020; BioMed Central; BMC
• Subjects: Animals; Breast cancer; breast neoplasms; Breast Neoplasms - drug therapy; Breast Neoplasms - epidemiology; Breast Neoplasms - pathology; Cancer; Cancer therapies; Causes of; Cell adhesion & migration; Chemicals; Chemoresistance; Chemotherapy; Contaminants; Development and progression; Dioxins; Disease Progression; Drug dosages; Drug resistance; Drug Resistance, Neoplasm; Drug therapy; Ecology, environment; Ecotoxicology; Endocrine disrupting chemicals; Endocrine disruptors; Environmental exposure; Environmental health; Environmental Pollutants - toxicity; Epidemiology; Female; Health; Health aspects; Humans; Invasiveness; Life Sciences; Ligands; Lymphatic system; Medical prognosis; Mesenchyme; Metastases; Metastasis; Molecular modelling; Organochlorine pesticides; PCB; Perfluoroalkyl acid; Persistent organic pollutants; Phenotypes; Pollutants; Polychlorinated biphenyls; Public health; Review; Risk analysis; Risk factors; Signal transduction; Signaling; Stem cells; Toxicants; Toxicology; Tumor cells; Tumors; Xenobiotics; France; Environmental exposure; Perfluoroalkyl acid; Organochlorine pesticides; Polychlorinated biphenyls; Breast cancer; Environmental pollutants; aryl hydrocarbon receptor; cancer stem cells; drug resistance; Endocrine disrupting chemicals; breast cancer; cancer stem cells; drug resistance

Breast cancer (BC) is one of the most common causes of cancer in the world and the second leading cause of cancer deaths among women. Mortality is associated mainly with the development of metastases. Identification of the mechanisms involved in metastasis formation is, therefore, a major public hea...