Evaluation of fecal microbiota transplantation in Parkinson's disease patients with constipation

• Published in: Microbial cell factories Vol. 20; no. 1; pp. 98 - 9
• Main Authors: Kuai, Xiao-yi, Yao, Xiao-han, Xu, Li-juan, Zhou, Yu-qing, Zhang, Li-ping, Liu, Yi, Pei, Shao-fang, Zhou, Chun-li
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.05.2021; BioMed Central; BMC
• Subjects: 16s rDNA sequencing; Abdomen; Abundance; Biochemistry; Care and treatment; Complications and side effects; Constipation; Deoxyribonucleic acid; Digestive system; DNA; DNA sequencing; Dysbacteriosis; Fecal microflora; Feces; FMT; Gastrointestinal diseases; Gastrointestinal tract; Gene sequencing; Gut microbiota; Health aspects; Intestinal microflora; Intestine; Laboratories; Lactulose; Metabolism; Microbiota; Microbiota (Symbiotic organisms); Microorganisms; Movement disorders; Neurodegenerative diseases; Pain; Parkinson's disease; Patient outcomes; Patients; Questionnaires; Signs and symptoms; Small intestine; Transplantation; China; Japan; Gut microbiota; FMT; 16s rDNA sequencing; Constipation; Parkinson’s disease

Parkinson’s disease (PD) is a neurodegenerative disorder and 70–80% of PD patients suffer from gastrointestinal dysfunction such as constipation. We aimed to assess the efficacy and safety of fecal microbiota transplantation (FMT) for treating PD related to gastrointestinal dysfunction. We conducted...