Delayed Cerebral Vasculopathy Following Cranial Radiation Therapy for Pediatric Tumors

• Published in: Pediatric neurology Vol. 50; no. 6; pp. 549 - 556
• Main Authors: Wang, Chenyang, Roberts, Kenneth B., Bindra, Ranjit S., Chiang, Veronica L., Yu, James B.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2014
• Subjects: Brain Neoplasms - radiotherapy; Cerebral Hemorrhage - epidemiology; Cerebral Hemorrhage - etiology; Cerebrovascular Disorders - epidemiology; Cerebrovascular Disorders - etiology; cerebrovasculopathy; Child; Humans; intracerebral hemorrhage; moyamoya; Moyamoya Disease - epidemiology; Moyamoya Disease - etiology; Neurology; Pediatrics; radiation; Radiotherapy - adverse effects; intracerebral hemorrhage; cerebrovasculopathy; moyamoya; radiation

Radiation-induced cerebrovascular injury is a well-known phenomenon. We analyze reported cases of delayed radiation-induced cerebrovasculopathy that present as moyamoya syndrome and/or intracerebral hemorrhage and to statistically analyze the relationship between radiation dose and the interval peri...