Anti-inflammatory effects of Lactobacillus johnsonii L531 in a pig model of Salmonella Infantis infection involves modulation of CCR6 + T cell responses and ER stress

Probiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus johnsonii L531, isolated from the colon of a clinically healthy weaned piglet, effectively prevented infection with Salmonella enterica serovar Infantis in...

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Published inVeterinary research (Paris) Vol. 51; no. 1; p. 26
Main Authors Yang, Gui-Yan, Xia, Bing, Su, Jin-Hui, He, Ting, Liu, Xiao, Guo, Liang, Zhang, Shuai, Zhu, Yao-Hong, Wang, Jiu-Feng
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 24.02.2020
BioMed Central
BMC
Subjects
Analysis
Anti-inflammatory drugs
Antimicrobial agents
Bacteria
Diarrhea
Enzymes
Ethylenediaminetetraacetic acid
Health care
Hogs
Infection
Infection control
Infections
Inflammation
Inflammatory bowel disease
Laboratory animals
Life Sciences
Lymphocytes
Microbiota
Probiotics
Proteins
Salmonella
Swine
T cells
United Kingdom
China
Beijing China
United Kingdom > UK
United States > US
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Abstract Probiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus johnsonii L531, isolated from the colon of a clinically healthy weaned piglet, effectively prevented infection with Salmonella enterica serovar Infantis in a pig model. Newly weaned piglets were intragastrically administered Lactobacillus johnsonii L531 at 1.0 × 10  CFU/day for 1 week before S. Infantis challenge. Pretreatment with L. johnsonii L531 lessened the severity of diarrhea and ileal inflammation in S. Infantis-infected piglets. Lactobacilli were more abundant in the ileum than jejunum after L. johnsonii L531 pretreatment. Treatment with L. johnsonii L531 reduced the abundance of total bacteria in the ileal mucosa and the production of lipocalin 2 in the jejunum of piglets challenged with Salmonella. Both intestinal morphology and transmission electron microscopy results indicated that L. johnsonii L531 alleviated intestinal tissue damage following S. Infantis challenge, especially in the villus and endoplasmic reticulum (ER). ER stress induced by S. Infantis was attenuated by L. johnsonii L531 treatment. The number of CD4 CCR6 T cells decreased following S. Infantis challenge, but the percentage of CCR6 IFNγ T cells in peripheral blood increased. In intestinal mesenteric lymph nodes, S. Infantis increased the proportion of CCR6 IFNγ T cells, whereas L. johnsonii L531 induced an increase in the proportion of CD4 CCR6 T cells in response to S. Infantis infection. Our data thus suggest that L. johnsonii L531 contributes to the maintenance of intestinal homeostasis by modulating T-cell responses and ER stress.
AbstractList AbstractProbiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus johnsonii L531, isolated from the colon of a clinically healthy weaned piglet, effectively prevented infection with Salmonella enterica serovar Infantis in a pig model. Newly weaned piglets were intragastrically administered Lactobacillus johnsonii L531 at 1.0 × 1010 CFU/day for 1 week before S. Infantis challenge. Pretreatment with L. johnsonii L531 lessened the severity of diarrhea and ileal inflammation in S. Infantis–infected piglets. Lactobacilli were more abundant in the ileum than jejunum after L. johnsonii L531 pretreatment. Treatment with L. johnsonii L531 reduced the abundance of total bacteria in the ileal mucosa and the production of lipocalin 2 in the jejunum of piglets challenged with Salmonella. Both intestinal morphology and transmission electron microscopy results indicated that L. johnsonii L531 alleviated intestinal tissue damage following S. Infantis challenge, especially in the villus and endoplasmic reticulum (ER). ER stress induced by S. Infantis was attenuated by L. johnsonii L531 treatment. The number of CD4− CCR6+ T cells decreased following S. Infantis challenge, but the percentage of CCR6− IFNγ+ T cells in peripheral blood increased. In intestinal mesenteric lymph nodes, S. Infantis increased the proportion of CCR6+ IFNγ+ T cells, whereas L. johnsonii L531 induced an increase in the proportion of CD4+ CCR6+ T cells in response to S. Infantis infection. Our data thus suggest that L. johnsonii L531 contributes to the maintenance of intestinal homeostasis by modulating T-cell responses and ER stress.
Probiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus johnsonii L531, isolated from the colon of a clinically healthy weaned piglet, effectively prevented infection with Salmonella enterica serovar Infantis in a pig model. Newly weaned piglets were intragastrically administered Lactobacillus johnsonii L531 at 1.0 × 10  CFU/day for 1 week before S. Infantis challenge. Pretreatment with L. johnsonii L531 lessened the severity of diarrhea and ileal inflammation in S. Infantis-infected piglets. Lactobacilli were more abundant in the ileum than jejunum after L. johnsonii L531 pretreatment. Treatment with L. johnsonii L531 reduced the abundance of total bacteria in the ileal mucosa and the production of lipocalin 2 in the jejunum of piglets challenged with Salmonella. Both intestinal morphology and transmission electron microscopy results indicated that L. johnsonii L531 alleviated intestinal tissue damage following S. Infantis challenge, especially in the villus and endoplasmic reticulum (ER). ER stress induced by S. Infantis was attenuated by L. johnsonii L531 treatment. The number of CD4 CCR6 T cells decreased following S. Infantis challenge, but the percentage of CCR6 IFNγ T cells in peripheral blood increased. In intestinal mesenteric lymph nodes, S. Infantis increased the proportion of CCR6 IFNγ T cells, whereas L. johnsonii L531 induced an increase in the proportion of CD4 CCR6 T cells in response to S. Infantis infection. Our data thus suggest that L. johnsonii L531 contributes to the maintenance of intestinal homeostasis by modulating T-cell responses and ER stress.
Probiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus johnsonii L531, isolated from the colon of a clinically healthy weaned piglet, effectively prevented infection with Salmonella enterica serovar Infantis in a pig model. Newly weaned piglets were intragastrically administered Lactobacillus johnsonii L531 at 1.0 × 1010 CFU/day for 1 week before S. Infantis challenge. Pretreatment with L. johnsonii L531 lessened the severity of diarrhea and ileal inflammation in S. Infantis–infected piglets. Lactobacilli were more abundant in the ileum than jejunum after L. johnsonii L531 pretreatment. Treatment with L. johnsonii L531 reduced the abundance of total bacteria in the ileal mucosa and the production of lipocalin 2 in the jejunum of piglets challenged with Salmonella. Both intestinal morphology and transmission electron microscopy results indicated that L. johnsonii L531 alleviated intestinal tissue damage following S. Infantis challenge, especially in the villus and endoplasmic reticulum (ER). ER stress induced by S. Infantis was attenuated by L. johnsonii L531 treatment. The number of CD4− CCR6+ T cells decreased following S. Infantis challenge, but the percentage of CCR6− IFNγ+ T cells in peripheral blood increased. In intestinal mesenteric lymph nodes, S. Infantis increased the proportion of CCR6+ IFNγ+ T cells, whereas L. johnsonii L531 induced an increase in the proportion of CD4+ CCR6+ T cells in response to S. Infantis infection. Our data thus suggest that L. johnsonii L531 contributes to the maintenance of intestinal homeostasis by modulating T-cell responses and ER stress.
Abstract Probiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus johnsonii L531, isolated from the colon of a clinically healthy weaned piglet, effectively prevented infection with Salmonella enterica serovar Infantis in a pig model. Newly weaned piglets were intragastrically administered Lactobacillus johnsonii L531 at 1.0 × 10 10  CFU/day for 1 week before S . Infantis challenge. Pretreatment with L. johnsonii L531 lessened the severity of diarrhea and ileal inflammation in S . Infantis–infected piglets. Lactobacilli were more abundant in the ileum than jejunum after L. johnsonii L531 pretreatment. Treatment with L. johnsonii L531 reduced the abundance of total bacteria in the ileal mucosa and the production of lipocalin 2 in the jejunum of piglets challenged with Salmonella . Both intestinal morphology and transmission electron microscopy results indicated that L. johnsonii L531 alleviated intestinal tissue damage following S . Infantis challenge, especially in the villus and endoplasmic reticulum (ER). ER stress induced by S . Infantis was attenuated by L. johnsonii L531 treatment. The number of CD4 − CCR6 + T cells decreased following S. Infantis challenge, but the percentage of CCR6 − IFNγ + T cells in peripheral blood increased. In intestinal mesenteric lymph nodes, S . Infantis increased the proportion of CCR6 + IFNγ + T cells, whereas L. johnsonii L531 induced an increase in the proportion of CD4 + CCR6 + T cells in response to S . Infantis infection. Our data thus suggest that L. johnsonii L531 contributes to the maintenance of intestinal homeostasis by modulating T-cell responses and ER stress.
Abstract Probiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus johnsonii L531, isolated from the colon of a clinically healthy weaned piglet, effectively prevented infection with Salmonella enterica serovar Infantis in a pig model. Newly weaned piglets were intragastrically administered Lactobacillus johnsonii L531 at 1.0 × 1010 CFU/day for 1 week before S. Infantis challenge. Pretreatment with L. johnsonii L531 lessened the severity of diarrhea and ileal inflammation in S. Infantis–infected piglets. Lactobacilli were more abundant in the ileum than jejunum after L. johnsonii L531 pretreatment. Treatment with L. johnsonii L531 reduced the abundance of total bacteria in the ileal mucosa and the production of lipocalin 2 in the jejunum of piglets challenged with Salmonella. Both intestinal morphology and transmission electron microscopy results indicated that L. johnsonii L531 alleviated intestinal tissue damage following S. Infantis challenge, especially in the villus and endoplasmic reticulum (ER). ER stress induced by S. Infantis was attenuated by L. johnsonii L531 treatment. The number of CD4− CCR6+ T cells decreased following S. Infantis challenge, but the percentage of CCR6− IFNγ+ T cells in peripheral blood increased. In intestinal mesenteric lymph nodes, S. Infantis increased the proportion of CCR6+ IFNγ+ T cells, whereas L. johnsonii L531 induced an increase in the proportion of CD4+ CCR6+ T cells in response to S. Infantis infection. Our data thus suggest that L. johnsonii L531 contributes to the maintenance of intestinal homeostasis by modulating T-cell responses and ER stress.
Probiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus johnsonii L531, isolated from the colon of a clinically healthy weaned piglet, effectively prevented infection with Salmonella enterica serovar Infantis in a pig model. Newly weaned piglets were intragastrically administered Lactobacillus johnsonii L531 at 1.0 × 10 10  CFU/day for 1 week before S . Infantis challenge. Pretreatment with L. johnsonii L531 lessened the severity of diarrhea and ileal inflammation in S . Infantis–infected piglets. Lactobacilli were more abundant in the ileum than jejunum after L. johnsonii L531 pretreatment. Treatment with L. johnsonii L531 reduced the abundance of total bacteria in the ileal mucosa and the production of lipocalin 2 in the jejunum of piglets challenged with Salmonella . Both intestinal morphology and transmission electron microscopy results indicated that L. johnsonii L531 alleviated intestinal tissue damage following S . Infantis challenge, especially in the villus and endoplasmic reticulum (ER). ER stress induced by S . Infantis was attenuated by L. johnsonii L531 treatment. The number of CD4 − CCR6 + T cells decreased following S. Infantis challenge, but the percentage of CCR6 − IFNγ + T cells in peripheral blood increased. In intestinal mesenteric lymph nodes, S . Infantis increased the proportion of CCR6 + IFNγ + T cells, whereas L. johnsonii L531 induced an increase in the proportion of CD4 + CCR6 + T cells in response to S . Infantis infection. Our data thus suggest that L. johnsonii L531 contributes to the maintenance of intestinal homeostasis by modulating T-cell responses and ER stress.
ArticleNumber 26
Audience Academic
Author Xia, Bing
Su, Jin-Hui
Wang, Jiu-Feng
He, Ting
Zhang, Shuai
Yang, Gui-Yan
Zhu, Yao-Hong
Liu, Xiao
Guo, Liang
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Cites_doi 10.1017/S0950268813001799
10.1186/1471-2407-11-229
10.3389/fmicb.2017.02705
10.1002/eji.200324347
10.1128/AEM.01419-13
10.1111/1346-8138.13227
10.1111/jgh.14362
10.4049/jimmunol.1302734
10.1002/bit.23282
10.3390/cells8030261
10.1038/nature05124
10.1016/j.taap.2012.07.005
10.3390/microorganisms6040117
10.1371/journal.pone.0040666
10.1038/35014014
10.1111/j.1574-6968.2009.01887.x
10.3389/fimmu.2017.00805
10.1016/j.yexcr.2010.12.018
10.3389/fcimb.2017.00323
10.1016/j.mayocp.2016.07.025
10.1016/j.yexcr.2011.07.008
10.1038/mi.2010.74
10.1128/AEM.03668-13
10.1038/sj.embor.7400779
10.1186/s13567-016-0355-8
10.1371/journal.pone.0220843
10.1186/s13567-015-0223-y
10.1016/S0022-1759(00)00209-X
10.1016/j.vetmic.2019.02.003
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References YL Lin (754_CR28) 2017; 8
GY Yang (754_CR12) 2017; 7
GI Solano-Aguilar (754_CR16) 2000; 241
S Keelara (754_CR2) 2013; 79
IL Hsin (754_CR24) 2012; 263
F Atassi (754_CR9) 2010; 304
D Zhou (754_CR15) 2015; 46
E Szegezdi (754_CR22) 2006; 7
W Zhang (754_CR4) 2017; 8
R Varona (754_CR29) 2003; 33
A Kaser (754_CR6) 2011; 317
NR Mahadevan (754_CR23) 2011; 11
GY Yang (754_CR13) 2016; 47
J van der Giessen (754_CR20) 2019; 8
T Duhen (754_CR26) 2014; 193
DH Kim (754_CR11) 2018; 34
D Shin (754_CR19) 2019; 14
CS Hau (754_CR25) 2016; 43
JH Su (754_CR3) 2018; 6
YH Zhu (754_CR17) 2014; 80
AW Paton (754_CR7) 2006; 443
R Bassal (754_CR1) 2014; 142
A Chakrabarti (754_CR8) 2011; 108
RD Eri (754_CR5) 2011; 4
T Ito (754_CR27) 2011; 317
XQ Li (754_CR14) 2012; 7
T He (754_CR10) 2019; 230
A Bertolotti (754_CR21) 2000; 2
EJ Krajicek (754_CR18) 2016; 91
References_xml – volume: 142
  start-page: 820
  year: 2014
  ident: 754_CR1
  publication-title: Epidemiol Infect
  doi: 10.1017/S0950268813001799
  contributor:
    fullname: R Bassal
– volume: 11
  start-page: 229
  year: 2011
  ident: 754_CR23
  publication-title: BMC Cancer
  doi: 10.1186/1471-2407-11-229
  contributor:
    fullname: NR Mahadevan
– volume: 8
  start-page: 2705
  year: 2017
  ident: 754_CR4
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2017.02705
  contributor:
    fullname: W Zhang
– volume: 33
  start-page: 2937
  year: 2003
  ident: 754_CR29
  publication-title: Eur J Immunol
  doi: 10.1002/eji.200324347
  contributor:
    fullname: R Varona
– volume: 79
  start-page: 5167
  year: 2013
  ident: 754_CR2
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.01419-13
  contributor:
    fullname: S Keelara
– volume: 43
  start-page: 785
  year: 2016
  ident: 754_CR25
  publication-title: J Dermatol
  doi: 10.1111/1346-8138.13227
  contributor:
    fullname: CS Hau
– volume: 34
  start-page: 178
  year: 2018
  ident: 754_CR11
  publication-title: J Gastroenterol Hepatol
  doi: 10.1111/jgh.14362
  contributor:
    fullname: DH Kim
– volume: 193
  start-page: 120
  year: 2014
  ident: 754_CR26
  publication-title: J Immunol
  doi: 10.4049/jimmunol.1302734
  contributor:
    fullname: T Duhen
– volume: 108
  start-page: 2777
  year: 2011
  ident: 754_CR8
  publication-title: Biotechnol Bioeng
  doi: 10.1002/bit.23282
  contributor:
    fullname: A Chakrabarti
– volume: 8
  start-page: E261
  year: 2019
  ident: 754_CR20
  publication-title: Cells
  doi: 10.3390/cells8030261
  contributor:
    fullname: J van der Giessen
– volume: 443
  start-page: 548
  year: 2006
  ident: 754_CR7
  publication-title: Nature
  doi: 10.1038/nature05124
  contributor:
    fullname: AW Paton
– volume: 263
  start-page: 330
  year: 2012
  ident: 754_CR24
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2012.07.005
  contributor:
    fullname: IL Hsin
– volume: 6
  start-page: E117
  year: 2018
  ident: 754_CR3
  publication-title: Microorganisms
  doi: 10.3390/microorganisms6040117
  contributor:
    fullname: JH Su
– volume: 7
  start-page: e40666
  year: 2012
  ident: 754_CR14
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0040666
  contributor:
    fullname: XQ Li
– volume: 2
  start-page: 326
  year: 2000
  ident: 754_CR21
  publication-title: Nat Cell Biol
  doi: 10.1038/35014014
  contributor:
    fullname: A Bertolotti
– volume: 304
  start-page: 29
  year: 2010
  ident: 754_CR9
  publication-title: FEMS Microbiol Lett
  doi: 10.1111/j.1574-6968.2009.01887.x
  contributor:
    fullname: F Atassi
– volume: 8
  start-page: 805
  year: 2017
  ident: 754_CR28
  publication-title: Front Immunol
  doi: 10.3389/fimmu.2017.00805
  contributor:
    fullname: YL Lin
– volume: 317
  start-page: 613
  year: 2011
  ident: 754_CR27
  publication-title: Exp Cell Res
  doi: 10.1016/j.yexcr.2010.12.018
  contributor:
    fullname: T Ito
– volume: 7
  start-page: 323
  year: 2017
  ident: 754_CR12
  publication-title: Front Cell Infect Microbiol
  doi: 10.3389/fcimb.2017.00323
  contributor:
    fullname: GY Yang
– volume: 91
  start-page: 1828
  year: 2016
  ident: 754_CR18
  publication-title: Mayo Clin Proc
  doi: 10.1016/j.mayocp.2016.07.025
  contributor:
    fullname: EJ Krajicek
– volume: 317
  start-page: 2772
  year: 2011
  ident: 754_CR6
  publication-title: Exp Cell Res
  doi: 10.1016/j.yexcr.2011.07.008
  contributor:
    fullname: A Kaser
– volume: 4
  start-page: 354
  year: 2011
  ident: 754_CR5
  publication-title: Mucosal Immunol
  doi: 10.1038/mi.2010.74
  contributor:
    fullname: RD Eri
– volume: 80
  start-page: 1787
  year: 2014
  ident: 754_CR17
  publication-title: Appl Environ Microbiol
  doi: 10.1128/AEM.03668-13
  contributor:
    fullname: YH Zhu
– volume: 7
  start-page: 880
  year: 2006
  ident: 754_CR22
  publication-title: EMBO Rep
  doi: 10.1038/sj.embor.7400779
  contributor:
    fullname: E Szegezdi
– volume: 47
  start-page: 71
  year: 2016
  ident: 754_CR13
  publication-title: Vet Res
  doi: 10.1186/s13567-016-0355-8
  contributor:
    fullname: GY Yang
– volume: 14
  start-page: e0220843
  year: 2019
  ident: 754_CR19
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0220843
  contributor:
    fullname: D Shin
– volume: 46
  start-page: 95
  year: 2015
  ident: 754_CR15
  publication-title: Vet Res
  doi: 10.1186/s13567-015-0223-y
  contributor:
    fullname: D Zhou
– volume: 241
  start-page: 185
  year: 2000
  ident: 754_CR16
  publication-title: J Immunol Methods
  doi: 10.1016/S0022-1759(00)00209-X
  contributor:
    fullname: GI Solano-Aguilar
– volume: 230
  start-page: 187
  year: 2019
  ident: 754_CR10
  publication-title: Vet Microbiol
  doi: 10.1016/j.vetmic.2019.02.003
  contributor:
    fullname: T He
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Snippet Probiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus johnsonii L531,...
Abstract Probiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus...
AbstractProbiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus...
Probiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus johnsonii L531,...
Abstract Probiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus...
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StartPage 26
SubjectTerms Analysis
Anti-inflammatory drugs
Antimicrobial agents
Bacteria
Diarrhea
Enzymes
Ethylenediaminetetraacetic acid
Health care
Hogs
Infection
Infection control
Infections
Inflammation
Inflammatory bowel disease
Laboratory animals
Life Sciences
Lymphocytes
Microbiota
Probiotics
Proteins
Salmonella
Swine
T cells
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Title Anti-inflammatory effects of Lactobacillus johnsonii L531 in a pig model of Salmonella Infantis infection involves modulation of CCR6 + T cell responses and ER stress
URI https://www.ncbi.nlm.nih.gov/pubmed/32093767
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https://pubmed.ncbi.nlm.nih.gov/PMC7041187
https://doaj.org/article/ac6631c7a99a46e68a3b1fd65ddd6e86
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