Nanoparticle-mediated synergistic chemoimmunotherapy for tailoring cancer therapy: recent advances and perspectives

• Published in: Journal of nanobiotechnology Vol. 19; no. 1; pp. 110 - 18
• Main Authors: Bagherifar, Rafieh, Kiaie, Seyed Hossein, Hatami, Zahra, Ahmadi, Armin, Sadeghnejad, Abdolvahid, Baradaran, Behzad, Jafari, Reza, Javadzadeh, Yousef
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 17.04.2021; BioMed Central; BMC
• Subjects: Antigens; Apoptosis; Biomarkers; Cancer; Cancer therapies; Care and treatment; Chemoimmunotherapy; Chemotherapy; Clinical trials; Cytokines; Cytotoxicity; Drugs; FDA approval; Gating; Health aspects; Immune system; Immunomodulation; Immunotherapy; Lung cancer; Lymphocytes; Melanoma; Metastasis; Methods; Monoclonal antibody; Mutation; Nanoparticles; Patients; Review; Signal transduction; T cell receptors; Tumorigenesis; Iran; Nanoparticles; Chemotherapy; Monoclonal antibody; Cytokines; Chemoimmunotherapy; Immunotherapy

Nowadays, a potent challenge in cancer treatment is considered the lack of efficacious strategy, which has not been able to significantly reduce mortality. Chemoimmunotherapy (CIT) as a promising approach in both for the first-line and relapsed therapy demonstrated particular benefit from two key ga...