Cell microencapsulation with synthetic polymers

• Published in: Journal of biomedical materials research. Part A Vol. 103; no. 2; pp. 846 - 859
• Main Author: Olabisi, Ronke M.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.02.2015; Wiley Subscription Services, Inc
• Subjects: Algae; Animals; Biodegradable Plastics - chemistry; Biodegradable Plastics - therapeutic use; Capsules; cell therapy; Cell- and Tissue-Based Therapy - methods; Cells, Immobilized; Cellular Microenvironment; Humans; Immune response; Mammals; microcapsule; microencapsulation; microsphere; Polymers; Review; synthetic polymer; synthetic polymer; microsphere; microcapsule; cell therapy; microencapsulation

The encapsulation of cells into polymeric microspheres or microcapsules has permitted the transplantation of cells into human and animal subjects without the need for immunosuppressants. Cell‐based therapies use donor cells to provide sustained release of a therapeutic product, such as insulin, and...