β-Cryptoxanthin modulates the response to phytosterols in post-menopausal women carrying NPC1L1 L272L and ABCG8 A632 V polymorphisms: an exploratory study

• Published in: Genes & nutrition Vol. 9; no. 5; p. 428
• Main Authors: Granado-Lorencio, F, de las Heras, L, Millán, C. San, Garcia-López, F. J, Blanco-Navarro, I, Pérez-Sacristán, B, Domínguez, G
• Format: Journal Article
• Language: English
• Published: Germany Springer-Verlag 01.09.2014; Springer Berlin Heidelberg
• Subjects: absorption; beta-cryptoxanthin; food technology; genes; genetic polymorphism; hypercholesterolemia; low density lipoprotein cholesterol; phytosterols; postmenopause; Research Paper; transporters; women

Phytosterol (PS) intake may be used for hypercholesterolaemia in some groups although the presence of non-responders is well known. Carotenoids and PS/cholesterol may compete for the same transporters during absorption. As part of a randomized, double-blind, crossover, multiple-dose supplementation...