Alkane biosynthesis by Aspergillus carbonarius ITEM 5010 through heterologous expression of Synechococcus elongatus acyl-ACP/CoA reductase and aldehyde deformylating oxygenase genes

• Published in: AMB Express Vol. 7; no. 1; pp. 18 - 9
• Main Authors: Sinha, Malavika, Weyda, István, Sørensen, Annette, Bruno, Kenneth S., Ahring, Birgitte K.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 05.01.2017; Springer Nature B.V; Springer
• Subjects: Advanced biofuels; Alkane biosynthesis; Aspergillus carbonarius; Aspergillus carbonarius ITEM 5010; BASIC BIOLOGICAL SCIENCES; Biomedical and Life Sciences; Biotechnology; Biotechnology & Applied Microbiology; Fungal transformation; Life Sciences; Microbial Genetics and Genomics; Microbiology; Original; Original Article; Synechococcus elongatus; ITEM 5010; Advanced biofuels; Alkane biosynthesis; Fungal transformation; Aspergillus carbonarius ITEM 5010

In this study we describe the heterologous expression of the recently identified cyanobacterial pathway for long chain alkane biosynthesis, involving the reduction of fatty acyl-ACP to fatty aldehyde and the subsequent conversion of this into alkanes, in the filamentous fungus Aspergillus carbonariu...