Severe Acute Respiratory Syndrome Coronavirus nsp1 Protein Suppresses Host Gene Expression by Promoting Host mRNA Degradation - Kamitani, Wataru; Narayanan, Krishna; Huang, Cheng; Lokugamage, Kumari; Ikegami, Tetsuro; Ito, Naoto; Kubo, Hideyuki; Makino, Shinji (Proceedings of the National Academy of Sciences - PNAS, 2006)
Keywords: Animals; Antibodies; Biological Sciences; Cell Line; Cell lines; Cells; Cercopithecus aethiops; Degradation; Dimerization; Gene Expression; Genes; Genes, Reporter - genetics; HEK293 cells; Humans; Interferon Regulatory Factor-3 - metabolism; Interferon-beta - genetics; Messenger RNA; Plasmids; Plasmids - genetics; Pneumonia; Protein synthesis; Proteins; Ribonucleic acid; RNA; RNA Stability; RNA, Messenger - genetics; SARS coronavirus; SARS Virus - genetics; SARS Virus - metabolism; Severe acute respiratory syndrome; Transfection; Vero cells; Viral Proteins - genetics; Viral Proteins - metabolism