Shortened Activated Partial Thromboplastin Time Is Associated With Acute Ischemic Stroke, Stroke Severity, and Neurological Worsening

• Published in: Journal of stroke and cerebrovascular diseases Vol. 24; no. 10; pp. 2270 - 2276
• Main Authors: Lin, Chun-Hsien, Kuo, Ya-Wen, Kuo, Chih-Yu, Huang, Yen-Chu, Hsu, Chia-Yu, Hsu, Huan-Lin, Lin, Ya-Hui, Wu, Chih-Ying, Huang, Ying-Chih, Lee, Meng, Yang, Hsin-Ta, Pan, Yi-Ting, Lee, Jiann-Der
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2015
• Subjects: activated partial thromboplastin time; Adult; Aged; Aged, 80 and over; association; Brain Ischemia - complications; Cardiovascular; Female; Humans; ischemic; Lipoproteins - metabolism; Male; Middle Aged; Nervous System Diseases - etiology; Neurology; Partial Thromboplastin Time; Retrospective Studies; risk; Stroke; Stroke - complications; Stroke - etiology; Thromboplastin - metabolism; Time Factors; ischemic; association; Stroke; risk; activated partial thromboplastin time

The role played by hemostasis in the pathogenesis of ischemic strokes is still controversial. The activated partial thromboplastin time (APTT) measures the time necessary to generate fibrin from initiation of the intrinsic pathway. In the present study, we looked for a possible association of ischem...