孟鲁司特治疗过敏性鼻炎的临床疗效及安全性
目的探讨孟鲁司特治疗过敏性鼻炎的安全性与有效性,为临床治疗提供一定的理论依据。方法选取2013年3月至2014年3月在该院接受治疗的116例过敏性鼻炎患者,采用随机、对照、双盲试验,根据就诊单双号将其分为观察组和对照组,各58例。观察组给予孟鲁司特钠片治疗,对照组给予安慰剂,疗程均为2周,统计两组患者的症状体征积分、疗效、生活质量评分及不良反应。结果观察组患者服用孟鲁司特后,各症状体征积分显著降低且显著低于对照组治疗后,显效率和总有效率均显著高于对照组,生活质量评分明显升高且显著高于对照组治疗后,差异均有统计学意义（P〈0.05）。观察组不良反应发生率为6.9%（4/58）,均较轻且未影响治疗...
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| Published in | 现代医药卫生 Vol. 32; no. 5; pp. 684 - 685 |
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| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
重庆市消防总队医院耳鼻咽喉科401133%重庆市中医院耳鼻咽喉科400000
2016
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1009-5519 |
| DOI | 10.3969/j.issn.1009-5519.2016.05.016 |
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| Abstract | 目的探讨孟鲁司特治疗过敏性鼻炎的安全性与有效性,为临床治疗提供一定的理论依据。方法选取2013年3月至2014年3月在该院接受治疗的116例过敏性鼻炎患者,采用随机、对照、双盲试验,根据就诊单双号将其分为观察组和对照组,各58例。观察组给予孟鲁司特钠片治疗,对照组给予安慰剂,疗程均为2周,统计两组患者的症状体征积分、疗效、生活质量评分及不良反应。结果观察组患者服用孟鲁司特后,各症状体征积分显著降低且显著低于对照组治疗后,显效率和总有效率均显著高于对照组,生活质量评分明显升高且显著高于对照组治疗后,差异均有统计学意义（P〈0.05）。观察组不良反应发生率为6.9%（4/58）,均较轻且未影响治疗。结论临床上应用孟鲁司特治疗过敏性鼻炎是安全、有效的。 |
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| AbstractList | 目的探讨孟鲁司特治疗过敏性鼻炎的安全性与有效性,为临床治疗提供一定的理论依据。方法选取2013年3月至2014年3月在该院接受治疗的116例过敏性鼻炎患者,采用随机、对照、双盲试验,根据就诊单双号将其分为观察组和对照组,各58例。观察组给予孟鲁司特钠片治疗,对照组给予安慰剂,疗程均为2周,统计两组患者的症状体征积分、疗效、生活质量评分及不良反应。结果观察组患者服用孟鲁司特后,各症状体征积分显著降低且显著低于对照组治疗后,显效率和总有效率均显著高于对照组,生活质量评分明显升高且显著高于对照组治疗后,差异均有统计学意义（P〈0.05）。观察组不良反应发生率为6.9%（4/58）,均较轻且未影响治疗。结论临床上应用孟鲁司特治疗过敏性鼻炎是安全、有效的。 目的 探讨孟鲁司特治疗过敏性鼻炎的安全性与有效性,为临床治疗提供一定的理论依据.方法 选取2013年3月至2014年3月在该院接受治疗的116例过敏性鼻炎患者,采用随机、对照、双盲试验,根据就诊单双号将其分为观察组和对照组,各58例.观察组给予孟鲁司特钠片治疗,对照组给予安慰剂,疗程均为2周,统计两组患者的症状体征积分、疗效、生活质量评分及不良反应.结果 观察组患者服用孟鲁司特后,各症状体征积分显著降低且显著低于对照组治疗后,显效率和总有效率均显著高于对照组,生活质量评分明显升高且显著高于对照组治疗后,差异均有统计学意义(P<0.05).观察组不良反应发生率为6.9%(4/58),均较轻且未影响治疗.结论 临床上应用孟鲁司特治疗过敏性鼻炎是安全、有效的. |
| Author | 张华艳 雷刚 |
| AuthorAffiliation | 重庆市消防总队医院耳鼻咽喉科,401133 重庆市中医院耳鼻咽喉科,400000 |
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| Author_FL | Leigang Zhang Huayan |
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| Author_xml | – sequence: 1 fullname: 张华艳 雷刚 |
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| DocumentTitleAlternate | Clinical efficacy and safety of montelukast in treatment of allergic rhinitis |
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| Keywords | 鼻炎/药物疗法 白三烯拮抗剂 治疗结果 乙酸盐类 喹啉类 |
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| Notes | ZhangHuayan ,Leigang（1. Department of Otorhinolaryngology , Chongqing Municipal Fire Corps Hospital, Chongqing 401133, China;2. Department of Otorhinolaryngology , Chongqing Municipal Hospital of Traditional Chinese Medicine, Chongqing 400000, China） Rhinitis/drug therapy ; Acetates ; Quinolines ; Leukotriene antagonists ; Treatment outcome Objective To discuss the safety and effectiveness of montelukast in the treatment of allergic rhinitis so as to provide certain theoretical basis for clinical treatment. Methods Totally 116 patients with allergic rhinitis treated in our hospital from March 2013 to March 2014 were selected and divided into the observation group and the control group according to the odd and even number at visiting clinic by the random,control and double blind trial,58 cases in each group. The observation group was given the treatment of montelukast sodium tablet and the control group was given placebos. The treatment course was two weeks in the two groups. The symptom and sign scores, curativ |
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| PublicationTitle | 现代医药卫生 |
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| PublicationYear | 2016 |
| Publisher | 重庆市消防总队医院耳鼻咽喉科401133%重庆市中医院耳鼻咽喉科400000 |
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| Snippet | ... 目的 探讨孟鲁司特治疗过敏性鼻炎的安全性与有效性,为临床治疗提供一定的理论依据.方法... |
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| SubjectTerms | 乙酸盐类 喹啉类 治疗结果 白三烯拮抗剂 鼻炎/药物疗法 |
| Title | 孟鲁司特治疗过敏性鼻炎的临床疗效及安全性 |
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