乳腺肿块微血管密度与血氧近红外光参数的实验研究

R737.9; 目的 从组织微血管分布密度初探乳腺肿块血氧近红外光参数的可靠性.方法用近红外光TBO-Ⅰ型双波长乳腺肿瘤检测仪,对检测的181例乳腺肿块进行近红外光血氧参数分类和病理切片检查明确肿块性质,并对其中20例恶性肿块和20例良性肿块进行免疫组织化学SP法检测乳腺肿块微血管密度,运用医学统计学方法分析近红外光血氧参数与微血管密度的相关性.结果 (1)28例高血乳腺肿块微血管密度值和血含量值分别为24.56±8.110和1.891±0.850,12例低血乳腺肿块微血管密度值和血含量值分别为17.98±8.729和0.698±0.283,两者比较存在显著性差异(P＜0.05);(2)40例...

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Published in肿瘤防治研究 Vol. 34; no. 1; pp. 51 - 53
Main Authors 黄烨, 陈登峰, 袁璐, 刘艳, 刘华, 张柳, 孔珺, 王虹
Format Journal Article
LanguageChinese
Published 434020,湖北,荆州,华中科技大学同济医学院附属荆州医院普外科 2007
Subjects
乳腺肿块
微血管密度
血氧近红外光参数
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ISSN1000-8578
DOI10.3971/j.issn.1000-8578.2007.01.016

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Abstract R737.9; 目的 从组织微血管分布密度初探乳腺肿块血氧近红外光参数的可靠性.方法用近红外光TBO-Ⅰ型双波长乳腺肿瘤检测仪,对检测的181例乳腺肿块进行近红外光血氧参数分类和病理切片检查明确肿块性质,并对其中20例恶性肿块和20例良性肿块进行免疫组织化学SP法检测乳腺肿块微血管密度,运用医学统计学方法分析近红外光血氧参数与微血管密度的相关性.结果 (1)28例高血乳腺肿块微血管密度值和血含量值分别为24.56±8.110和1.891±0.850,12例低血乳腺肿块微血管密度值和血含量值分别为17.98±8.729和0.698±0.283,两者比较存在显著性差异(P＜0.05);(2)40例乳腺肿块的微血管密度值与近红外光血含量值直线相关系数为r=0.4208(P＜0.05).结论乳腺良、恶性肿块局部微血管密度与其血含量近红外检测参数存在相关性,说明了近红外光血含量检测参数作为诊断乳腺癌标准的可靠性.
AbstractList R737.9; 目的 从组织微血管分布密度初探乳腺肿块血氧近红外光参数的可靠性.方法用近红外光TBO-Ⅰ型双波长乳腺肿瘤检测仪,对检测的181例乳腺肿块进行近红外光血氧参数分类和病理切片检查明确肿块性质,并对其中20例恶性肿块和20例良性肿块进行免疫组织化学SP法检测乳腺肿块微血管密度,运用医学统计学方法分析近红外光血氧参数与微血管密度的相关性.结果 (1)28例高血乳腺肿块微血管密度值和血含量值分别为24.56±8.110和1.891±0.850,12例低血乳腺肿块微血管密度值和血含量值分别为17.98±8.729和0.698±0.283,两者比较存在显著性差异(P＜0.05);(2)40例乳腺肿块的微血管密度值与近红外光血含量值直线相关系数为r=0.4208(P＜0.05).结论乳腺良、恶性肿块局部微血管密度与其血含量近红外检测参数存在相关性,说明了近红外光血含量检测参数作为诊断乳腺癌标准的可靠性.
Author 王虹
刘艳
黄烨
张柳
刘华
孔珺
陈登峰
袁璐
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LIU yian
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KONG jun
CHEN Deng-feng
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YUAN Lu
ZHANG liu
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微血管密度
血氧近红外光参数
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Title 乳腺肿块微血管密度与血氧近红外光参数的实验研究
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