TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea

• Published in: Chinese medicine Vol. 18; no. 1; pp. 60 - 17
• Main Authors: Li, Xiaoli, Yu, Xin, Gao, Yuan, Zhao, Wenqian, Wang, Yajuan, Yu, Fei, Fu, Chunli, Gao, Haiqing, Cheng, Mei, Li, Baoying
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 24.05.2023; BioMed Central; BMC
• Subjects: 1-Phosphatidylinositol 3-kinase; AKT protein; Analysis; Antibodies; Antioxidants; Apoptosis; Bleomycin; Chromatography; Ferroptosis; Fibrosis; Ginseng; Ginseng honeysuckle superfine powdered tea; Inflammation; Ions; Kinases; Lung diseases; Lungs; Medical research; Network pharmacology; p53 Protein; Peptides; Pharmacology; Polyphenols; Powders; Proteins; Proteomics; Pulmonary fibrosis; Serum pharmacochemistry; Signal transduction; Software; Therapeutic targets; Trachea; Tumor proteins; China; United States > US; Ginseng honeysuckle superfine powdered tea; Network pharmacology; Pulmonary fibrosis; Proteomics; Serum pharmacochemistry

Pulmonary fibrosis (PF) is a chronic and potentially fatal lung disease and disorder. Although the active ingredients of ginseng honeysuckle superfine powdered tea (GHSPT) have been proven to have anti-inflammatory and antioxidant effects, the mechanism of GHSPT on PF remains unclear. The present st...